Intensity-Modulated Radiation Therapy for Rectal Carcinoma Can Reduce Treatment Breaks and Emergency Department Visits
المؤلفون المشاركون
Azad, Nilofer S.
Haffty, Bruce G.
Jabbour, Salma K.
Nagda, Suneel N.
Herman, Joseph M.
Gearhart, Susan L.
Moss, Rebecca A.
Chandra, Ravi A.
Levinson, Lydia L.
Patel, Shyamal
Wild, Aaron T.
Poplin, Elizabeth
Moore, Dirk F.
Tuli, Richard
Tunceroglu, Ahmet
Chen, Chunxia
Altoos, Taghrid
المصدر
International Journal of Surgical Oncology
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-08-13
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Purpose.
To compare the acute toxicities of IMRT to 3D-conformal radiation therapy (3DCRT) in the treatment of rectal cancer.
Methods and Materials.
Eighty-six patients with rectal cancer preoperatively treated with IMRT (n=30) and 3DCRT (n=56) were retrospectively reviewed.
Rates of acute toxicity between IMRT and 3DCRT were compared for anorexia, dehydration, diarrhea, nausea, vomiting, weight loss, radiation dermatitis, fatigue, pain, urinary frequency, and blood counts.
Fisher's exact test and chi-square analysis were applied to detect statistical differences in incidences of toxicity between these two groups of patients.
Results.
There were fewer hospitalizations and emergency department visits in the group treated with IMRT compared with 3DCRT (P=0.005) and no treatment breaks with IMRT compared to 20% with 3DCRT (P=0.0002).
Patients treated with IMRT had a significant reduction in grade ≥3 toxicities versus grade ≤2 toxicities (P=0.016) when compared to 3DCRT.
The incidence of grade ≥3 diarrhea was 9% among 3DCRT patients compared to 3% among IMRT patients (P=0.31).
Conclusions.
IMRT for rectal cancer can reduce treatment breaks, emergency department visits, hospitalizations, and all grade ≥3 toxicities compared to 3DCRT.
Further evaluation and followup is warranted to determine late toxicities and long-term results of IMRT.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Jabbour, Salma K.& Patel, Shyamal& Herman, Joseph M.& Wild, Aaron T.& Nagda, Suneel N.& Altoos, Taghrid…[et al.]. 2012. Intensity-Modulated Radiation Therapy for Rectal Carcinoma Can Reduce Treatment Breaks and Emergency Department Visits. International Journal of Surgical Oncology،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-505796
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Jabbour, Salma K.…[et al.]. Intensity-Modulated Radiation Therapy for Rectal Carcinoma Can Reduce Treatment Breaks and Emergency Department Visits. International Journal of Surgical Oncology No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-505796
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Jabbour, Salma K.& Patel, Shyamal& Herman, Joseph M.& Wild, Aaron T.& Nagda, Suneel N.& Altoos, Taghrid…[et al.]. Intensity-Modulated Radiation Therapy for Rectal Carcinoma Can Reduce Treatment Breaks and Emergency Department Visits. International Journal of Surgical Oncology. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-505796
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-505796
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر