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Permanent Sensorineural Deafness in a Patient with Chronic Myelogenous Leukemia Secondary to Intracranial Hemorrhage
المؤلفون المشاركون
Levin, Miles B.
Hussain, Adnan
Kapur, Sakshi
Wax, Michael
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-12-03
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
A 52-year-old male presented with tinnitus and fullness in left ear for one day.
Workup revealed a white blood cell count of 685×103/μL with marked increase in granulocyte series and myeloid precursors on peripheral smear.
The initial impression was chronic myelogenous leukemia with hyperleukocytosis, and patient was started on hydration, hydroxyurea, and allopurinol.
Patient tolerated bone marrow biopsy well but continued to bleed excessively from the biopsy site.
Results confirmed Philadelphia chromosome positive chronic myelogenous leukemia (chronic phase).
On day three of hospitalization, patient developed sudden slurred speech along with shaking movements involving extremities.
Magnetic resonance imaging revealed multiple hemorrhages throughout the brain.
Hydroxyurea was continued until insurance coverage for nilotinib was getting approved.
On day nine of hospitalization, patient developed sudden bilateral sensorineural deafness.
Repeat magnetic resonance imaging revealed multiple new hemorrhages throughout the brain.
Computer tomography of the temporal bones showed inflammatory changes in right and left mastoid cells.
Nilotinib was started on day eleven of hospitalization.
Patient’s white blood cell count continued to decrease, but there was no improvement in hearing.
Four months later, patient was treated with bilateral transmastoid cochlear implants.
This case highlights permanent deafness as a hemorrhagic complication secondary to chronic myelogenous leukemia.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kapur, Sakshi& Wax, Michael& Levin, Miles B.& Hussain, Adnan. 2013. Permanent Sensorineural Deafness in a Patient with Chronic Myelogenous Leukemia Secondary to Intracranial Hemorrhage. Case Reports in Hematology،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-506084
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kapur, Sakshi…[et al.]. Permanent Sensorineural Deafness in a Patient with Chronic Myelogenous Leukemia Secondary to Intracranial Hemorrhage. Case Reports in Hematology No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-506084
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kapur, Sakshi& Wax, Michael& Levin, Miles B.& Hussain, Adnan. Permanent Sensorineural Deafness in a Patient with Chronic Myelogenous Leukemia Secondary to Intracranial Hemorrhage. Case Reports in Hematology. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-506084
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-506084
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