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Irinotecan Plus S-1 Followed by Hepatectomy for a Patient with Initially Unresectable Colorectal Liver Metastases, Who Showed Severe Drug Rash with Oxaliplatin Plus 5-FU and Leucovorin (FOLFOX)
المؤلفون المشاركون
Miyamoto, Yuji
Beppu, Toru
Watanabe, Masayuki
Hayashi, Hiromitsu
Sakamoto, Yasuo
Nitta, Hidetoshi
Komori, Hiroyuki
Baba, Hideo
Imai, Katsunori
المصدر
Case Reports in Gastrointestinal Medicine
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-06-17
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
For unresectable colorectal liver metastases (CRLM), hepatic resection with or without chemotherapy is the only curative treatment that sufficiently achieves long-term survival.
However, occasional severe allergic responses to anticancer drugs necessitate treatment discontinuation.
A 45-year-old woman presented with metachronous unresectable colorectal liver metastases.
Chemotherapy with oxaliplatin plus 5-FU and leucovorin (FOLFOX) was initiated, but severe allergic dermatitis developed after the second cycle.
Although she reported no prior history of adverse reactions to tegafur-uracil, a drug lymphocyte stimulation test showed an allergic response to 5-FU.
We subsequently replaced with Irinotecan plus S-1 (IRIS) chemotherapy which was well tolerated and resulted in a partial response after 3 cycles.
As a result, right trisectionectomy was successfully performed and no recurrence was detected in the following 3 years.
A severe allergic reaction to intravenous 5-FU-containing drug regimens can be successfully alleviated by switching to S-1-containing regimens such as IRIS or S-1 plus oxaliplatin (SOX).
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Komori, Hiroyuki& Beppu, Toru& Sakamoto, Yasuo& Miyamoto, Yuji& Hayashi, Hiromitsu& Imai, Katsunori…[et al.]. 2014. Irinotecan Plus S-1 Followed by Hepatectomy for a Patient with Initially Unresectable Colorectal Liver Metastases, Who Showed Severe Drug Rash with Oxaliplatin Plus 5-FU and Leucovorin (FOLFOX). Case Reports in Gastrointestinal Medicine،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-507043
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Komori, Hiroyuki…[et al.]. Irinotecan Plus S-1 Followed by Hepatectomy for a Patient with Initially Unresectable Colorectal Liver Metastases, Who Showed Severe Drug Rash with Oxaliplatin Plus 5-FU and Leucovorin (FOLFOX). Case Reports in Gastrointestinal Medicine No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-507043
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Komori, Hiroyuki& Beppu, Toru& Sakamoto, Yasuo& Miyamoto, Yuji& Hayashi, Hiromitsu& Imai, Katsunori…[et al.]. Irinotecan Plus S-1 Followed by Hepatectomy for a Patient with Initially Unresectable Colorectal Liver Metastases, Who Showed Severe Drug Rash with Oxaliplatin Plus 5-FU and Leucovorin (FOLFOX). Case Reports in Gastrointestinal Medicine. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-507043
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-507043
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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