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Acute and Long-Term Effects of Noise Exposure on the Neuronal Spontaneous Activity in Cochlear Nucleus and Inferior Colliculus Brain Slices
المؤلفون المشاركون
Ernst, Arne
Ryll, Jana
Basta, Dietmar
Götze, Romy
Gröschel, Moritz
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-07-07
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Noise exposure leads to an immediate hearing loss and is followed by a long-lasting permanent threshold shift, accompanied by changes of cellular properties within the central auditory pathway.
Electrophysiological recordings have demonstrated an upregulation of spontaneous neuronal activity.
It is still discussed if the observed effects are related to changes of peripheral input or evoked within the central auditory system.
The present study should describe the intrinsic temporal patterns of single-unit activity upon noise-induced hearing loss of the dorsal and ventral cochlear nucleus (DCN and VCN) and the inferior colliculus (IC) in adult mouse brain slices.
Recordings showed a slight, but significant, elevation in spontaneous firing rates in DCN and VCN immediately after noise trauma, whereas no differences were found in IC.
One week postexposure, neuronal responses remained unchanged compared to controls.
At 14 days after noise trauma, intrinsic long-term hyperactivity in brain slices of the DCN and the IC was detected for the first time.
Therefore, increase in spontaneous activity seems to develop within the period of two weeks, but not before day 7.
The results give insight into the complex temporal neurophysiological alterations after noise trauma, leading to a better understanding of central mechanisms in noise-induced hearing loss.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gröschel, Moritz& Ryll, Jana& Götze, Romy& Ernst, Arne& Basta, Dietmar. 2014. Acute and Long-Term Effects of Noise Exposure on the Neuronal Spontaneous Activity in Cochlear Nucleus and Inferior Colliculus Brain Slices. BioMed Research International،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-507297
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gröschel, Moritz…[et al.]. Acute and Long-Term Effects of Noise Exposure on the Neuronal Spontaneous Activity in Cochlear Nucleus and Inferior Colliculus Brain Slices. BioMed Research International No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-507297
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gröschel, Moritz& Ryll, Jana& Götze, Romy& Ernst, Arne& Basta, Dietmar. Acute and Long-Term Effects of Noise Exposure on the Neuronal Spontaneous Activity in Cochlear Nucleus and Inferior Colliculus Brain Slices. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-507297
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-507297
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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