Smart Magnetically Responsive Hydrogel Nanoparticles Prepared by a Novel Aerosol-Assisted Method for Biomedical and Drug Delivery Applications
المؤلفون المشاركون
El-Sherbiny, Ibrahim M.
Smyth, Hugh D. C.
المصدر
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-02-21
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
العلوم الهندسية و تكنولوجيا المعلومات
الكيمياء
هندسة مدنية
الملخص EN
We have developed a novel spray gelation-based method to synthesize a new series of magnetically responsive hydrogel nanoparticles for biomedical and drug delivery applications.
The method is based on the production of hydrogel nanoparticles from sprayed polymeric microdroplets obtained by an air-jet nebulization process that is immediately followed by gelation in a crosslinking fluid.
Oligoguluronate (G-blocks) was prepared through the partial acid hydrolysis of sodium alginate.
PEG-grafted chitosan was also synthesized and characterized (FTIR, EA, and DSC).
Then, magnetically responsive hydrogel nanoparticles based on alginate and alginate/G-blocks were synthesized via aerosolization followed by either ionotropic gelation or both ionotropic and polyelectrolyte complexation using CaCl2 or PEG-g-chitosan/CaCl2 as crosslinking agents, respectively.
Particle size and dynamic swelling were determined using dynamic light scattering (DLS) and microscopy.
Surface morphology of the nanoparticles was examined using SEM.
The distribution of magnetic cores within the hydrogels nanoparticles was also examined using TEM.
In addition, the iron and calcium contents of the particles were estimated using EDS.
Spherical magnetic hydrogel nanoparticles with average particle size of 811 ± 162 to 941 ± 2 nm were obtained.
This study showed that the developed method is promising for the manufacture of hydrogel nanoparticles, and it represents a relatively simple and potential low-cost system.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
El-Sherbiny, Ibrahim M.& Smyth, Hugh D. C.. 2011. Smart Magnetically Responsive Hydrogel Nanoparticles Prepared by a Novel Aerosol-Assisted Method for Biomedical and Drug Delivery Applications. Journal of Nanomaterials،Vol. 2011, no. 2011, pp.1-13.
https://search.emarefa.net/detail/BIM-507412
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
El-Sherbiny, Ibrahim M.& Smyth, Hugh D. C.. Smart Magnetically Responsive Hydrogel Nanoparticles Prepared by a Novel Aerosol-Assisted Method for Biomedical and Drug Delivery Applications. Journal of Nanomaterials No. 2011 (2011), pp.1-13.
https://search.emarefa.net/detail/BIM-507412
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
El-Sherbiny, Ibrahim M.& Smyth, Hugh D. C.. Smart Magnetically Responsive Hydrogel Nanoparticles Prepared by a Novel Aerosol-Assisted Method for Biomedical and Drug Delivery Applications. Journal of Nanomaterials. 2011. Vol. 2011, no. 2011, pp.1-13.
https://search.emarefa.net/detail/BIM-507412
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-507412
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر