Lymph Node Harvest in Dukes' A Cancer Pathologist May Need to Consider Fat Dissolving Technique : An Observational Study

الملخص EN

Background.

National institute of clinical excellence (NICE) recommends that a median of 12 lymph nodes be examined in patients operated on with curative intent- to- treat colorectal cancer (CRC).

Patients with lymph node harvest less than this may be considered under staged and may receive adjuvant chemotherapy.

The aim of our study was to ascertain median number of lymph nodes examined in early colorectal cancers.

Method.

Patients undergoing colorectal resection between June 2007 and May 2008 were identified and pathological staging obtained using pathology database.

Results.

146 patients underwent standardised laparoscopic or open resection of colorectal cancers during this period.

Overall median number of lymph nodes harvested/patient was 14 (3–40).

When analysed by stage, median number of lymph nodes harvested in Dukes' A, B, and C cancers was 10, 14, and 15, respectively.

11/18 (61%) patients with Dukes’ A carcinoma had lymph node harvest of less than 12 compared with 15/55 (27%) patients with Dukes’ B.

Conclusion.

Lymph node harvest in Dukes' A cancers using standard techniques tends to be low.

Pathologists may have to consider special techniques in harvesting lymph nodes for early colorectal cancers.