Protective Effects of Chinese Traditional Medicine Buyang Huanwu Decoction on Myocardial Injury
المؤلفون المشاركون
Fang, Zhiyuan
Shi, Xiaolian
Zhang, Hui
Lin, Rong
Ji, Qiaoli
Lin, Qinqin
Liu, Yu
Yang, Guangde
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-06-05
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Many clinical studies have reported that Buyang Huanwu Decoction (BYHWD) has a protective effect on ischemic heart disease (IHD).
In the present study, the protective effect of BYHWD on myocardial ischemia was investigated.
Different doses of BYHWD and Compound Danshen Dropping Pills (CDDP) were lavaged to rats, respectively, isoproterenol (ISO) was intraperitoneally injected in to all animals to induce myocardial ischemia except the control group.
Electrocardiogram (ECG) of each animal was recorded; activities of lactate dehydrogenase (LDH), creatine kinase (CK) and aspartate aminotransferase (AST) in serum were detected.
As the results of ECG showed, pre-treatment with BYHWD inhibited ischemic myocardial injury, and the activities of LDH, CK and AST were lower than those in the myocardial ischemia model group, which suggests that BYHWD rescues the myocardium from ischemia status.
To research the potential mechanism, the level of nitric oxide (NO), nitric oxide syntheses (NOS) and inducible nitric oxide syntheses (iNOS), the expression of iNOS and ligand of cluster of differentiation 40 (CD40L) were detected.
The results revealed that BYHWD significantly decreased the level of NO, NOS and iNOS in serum.
Moreover, BYHWD decreased the expression of iNOS and CD40L in myocardial tissues.
These results indicate that the protective effect of BYHWD on myocardial ischemia and mechanism are associated with inhibition of iNOS and CD40L expression.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yang, Guangde& Fang, Zhiyuan& Liu, Yu& Zhang, Hui& Shi, Xiaolian& Ji, Qiaoli…[et al.]. 2011. Protective Effects of Chinese Traditional Medicine Buyang Huanwu Decoction on Myocardial Injury. Evidence-Based Complementary and Alternative Medicine،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-509050
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yang, Guangde…[et al.]. Protective Effects of Chinese Traditional Medicine Buyang Huanwu Decoction on Myocardial Injury. Evidence-Based Complementary and Alternative Medicine No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-509050
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yang, Guangde& Fang, Zhiyuan& Liu, Yu& Zhang, Hui& Shi, Xiaolian& Ji, Qiaoli…[et al.]. Protective Effects of Chinese Traditional Medicine Buyang Huanwu Decoction on Myocardial Injury. Evidence-Based Complementary and Alternative Medicine. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-509050
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-509050
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر