Heterogeneity of Radiological Spectrum in Tacrolimus-Associated Encephalopathy after Lung Transplantation
المؤلفون المشاركون
Qin, Xinyue
Wu, Qisi
Marescaux, Christian
Yang, Jun
Kessler, Romain
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-05-27
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Background.
Tacrolimus-associated encephalopathy (TAC-E) is usually described under the term of posterior reversible encephalopathy syndrome (PRES).
However, a large amount of data has suggested that TAC-E is not a homogenous entity: indeed, TAC-E which is often presented with atypical and potentially misleading imaging characteristics does not always correspond to PRES.
Objective.
We aimed to identify the spectrum of brain MR imaging of TAC-E and discuss the underlying pathophysiological features.
Methods.
From September 2008 to October 2010, the neurological statuses of 45 patients, who underwent lung transplantation with TAC as posttransplantation immunosuppressive therapy, were regularly assessed in a prospective study.
MRI was repeatedly performed, until recovery, in patients who developed central neurological symptoms.
Results.
Symptoms suggestive of encephalopathy occurred in five out of 45 patients (11.1%).
According to our MRI study, two patients presented with reversible bilateral and relatively symmetric subcortical white matter edema with proximal vasospasms on MRA; however, three other patients were characterized by coexistence of two different lesions including laminar cortical infarcts with hemorrhagic transformation not typically found in PRES and reversible deep white matter edema, associated with distal vasospasms on MRA.
Conclusions.
It is considered that the mechanism of TAC-E would be more heterogenous than commonly perceived.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wu, Qisi& Marescaux, Christian& Qin, Xinyue& Kessler, Romain& Yang, Jun. 2014. Heterogeneity of Radiological Spectrum in Tacrolimus-Associated Encephalopathy after Lung Transplantation. Behavioural Neurology،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-509199
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wu, Qisi…[et al.]. Heterogeneity of Radiological Spectrum in Tacrolimus-Associated Encephalopathy after Lung Transplantation. Behavioural Neurology No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-509199
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wu, Qisi& Marescaux, Christian& Qin, Xinyue& Kessler, Romain& Yang, Jun. Heterogeneity of Radiological Spectrum in Tacrolimus-Associated Encephalopathy after Lung Transplantation. Behavioural Neurology. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-509199
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-509199
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر