Identifying Patients Who May Be Candidates for a Clinical Trial of Salvage Accelerated Partial Breast Irradiation after Previous Whole Breast Irradiation
المؤلفون المشاركون
Cohen, Randi J.
Tianyu, Li
Bleicher, Richard J.
Freedman, Gary M.
Li, Linna
Anderson, Penny R.
Goldstein, Lori J.
المصدر
International Journal of Breast Cancer
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-12-03
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background and Objectives.
Accelerated partial breast irradiation (APBI) has been proposed as an alternative to salvage mastectomy for patients with ipsilateral breast tumor recurrence (IBTR) after prior breast conservation.
We studied factors that are associated with a more favorable local recurrence profile that could make certain patients eligible for APBI.
Methods.
Between 1980 and 2005, 157 Stage 0–II breast cancer patients had an IBTR treated by mastectomy.
Clinical and pathological features were analyzed to identify factors associated with favorable IBTR defined as unifocal DCIS or T1 ≤ 2 cm, without skin involvement, and >2 year interval from initial treatment.
Results.
Median followup was 140 months and time to recurrence was 73 months.
Clinical stage distribution at recurrence was DCIS in 32 pts (20%), T1 in 90 pts (57%), T2 in 14 pts (9%), T3 in 4 pts (3%), and T4 in 9 pts (6%).
IBTR was classified as favorable in 71%.
Clinical stage of IBTR predicted for pathologic stage –95% of patients with clinical T1 IBTR had pathologic T1 disease at salvage mastectomy (P<0.0001).
Conclusions.
Clinical stage at presentation strongly correlated with pathologic stage at mastectomy.
More than 70% of recurrences were favorable and may be appropriate candidates for salvage APBI trials.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Li, Linna& Tianyu, Li& Cohen, Randi J.& Anderson, Penny R.& Goldstein, Lori J.& Bleicher, Richard J.…[et al.]. 2012. Identifying Patients Who May Be Candidates for a Clinical Trial of Salvage Accelerated Partial Breast Irradiation after Previous Whole Breast Irradiation. International Journal of Breast Cancer،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-509688
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Li, Linna…[et al.]. Identifying Patients Who May Be Candidates for a Clinical Trial of Salvage Accelerated Partial Breast Irradiation after Previous Whole Breast Irradiation. International Journal of Breast Cancer No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-509688
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Li, Linna& Tianyu, Li& Cohen, Randi J.& Anderson, Penny R.& Goldstein, Lori J.& Bleicher, Richard J.…[et al.]. Identifying Patients Who May Be Candidates for a Clinical Trial of Salvage Accelerated Partial Breast Irradiation after Previous Whole Breast Irradiation. International Journal of Breast Cancer. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-509688
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-509688
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر