Stratified Threshold Values of QuantiFERON Assay for Diagnosing Tuberculosis Infection in Immunocompromised Populations
المؤلفون المشاركون
Hoshino, Yoshihiko
Shoji, Syunsuke
Nakajima, Yutsuki
Nagai, Hideaki
Ariga, Haruyuki
Kurashima, Atsuyuki
المصدر
Tuberculosis Research and Treatment
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-06-27
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Background.
The detection of latent tuberculosis (TB) is essential for TB control, but T-cell assay might be influenced by degree of immunosuppression.
The relationship between immunocompetence and interferon (IFN)-γ response in QuantiFERON-TB Gold (QFT) is uncertain, especially in HIV-negative populations.
Methods and Results.
QFT has been performed for healthy subjects and TB suspected patients.
Of 3017 patients, 727 were diagnosed as pulmonary TB by culture.
The absolute number of blood lymphocyte in TB patients was significantly associated with QFT.
Definitive TB patients were divided into eight groups according to lymphocyte counts.
For each subgroup, receiver operating characteristic curve analysis was conducted from 357 healthy control subjects.
The optimal cut-off for the patient group with adequate lymphocyte counts was found, but this was reduced for lymphocytopenia.
Conclusions.
The lymphocyte count was positively associated with QFT.
Positive criteria should be calibrated in consideration of cell-mediated immunocompetence and risk of progression to active TB.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ariga, Haruyuki& Nagai, Hideaki& Kurashima, Atsuyuki& Hoshino, Yoshihiko& Shoji, Syunsuke& Nakajima, Yutsuki. 2011. Stratified Threshold Values of QuantiFERON Assay for Diagnosing Tuberculosis Infection in Immunocompromised Populations. Tuberculosis Research and Treatment،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-509937
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ariga, Haruyuki…[et al.]. Stratified Threshold Values of QuantiFERON Assay for Diagnosing Tuberculosis Infection in Immunocompromised Populations. Tuberculosis Research and Treatment No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-509937
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ariga, Haruyuki& Nagai, Hideaki& Kurashima, Atsuyuki& Hoshino, Yoshihiko& Shoji, Syunsuke& Nakajima, Yutsuki. Stratified Threshold Values of QuantiFERON Assay for Diagnosing Tuberculosis Infection in Immunocompromised Populations. Tuberculosis Research and Treatment. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-509937
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-509937
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر