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Treatment Choices Based on OncotypeDx in the Breast Oncology Care Setting
المؤلفون المشاركون
Han, Hyo S.
Lipkus, Isaac
Wilson, Tobi
Acs, Geza
Malo, Teri L.
Vadaparampil, Susan T.
المصدر
Journal of Cancer Epidemiology
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-08-13
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Introduction.
This study aimed to evaluate whether OncotypeDx test results predict receipt of adjuvant chemotherapy in breast cancer patients who received an OncotypeDx recurrence score (RS).
Materials and Methods.
Pathology records were used to identify breast cancer patients who had OncotypeDx testing between December 2004 and January 2009 (n=118).
Patient sociodemographic information, tumor characteristics, RS, and treatment-specific data were collected via chart review.
RS was classified as follows: low (RS≤17), intermediate (RS = 18–30), or high (RS≥31).
Bivariate analyses were conducted to investigate the relationship between adjuvant chemotherapy receipt and each sociodemographic and clinical characteristic; significant sociodemographic and clinical variables were included in a multivariable logistic regression model.
Results.
In multivariable analysis controlling for tumor size, histologic grade, and nuclear grade, only RS remained significantly associated with chemotherapy uptake.
Relative to low RS, an intermediate (adjusted odds ratio [AOR], 21.24; 95% confidence interval [CI], 3.62–237.52) or high (AOR, 15.07; 95% CI, 1.28–288.21) RS was associated with a greater odds of chemotherapy uptake.
Discussion.
Results indicate that RS was significantly associated with adjuvant chemotherapy uptake, suggesting that OncotypeDx results were used to inform treatment decision making, although it is unclear if and how the information was conveyed to patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Malo, Teri L.& Lipkus, Isaac& Wilson, Tobi& Han, Hyo S.& Acs, Geza& Vadaparampil, Susan T.. 2012. Treatment Choices Based on OncotypeDx in the Breast Oncology Care Setting. Journal of Cancer Epidemiology،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-510018
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Malo, Teri L.…[et al.]. Treatment Choices Based on OncotypeDx in the Breast Oncology Care Setting. Journal of Cancer Epidemiology No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-510018
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Malo, Teri L.& Lipkus, Isaac& Wilson, Tobi& Han, Hyo S.& Acs, Geza& Vadaparampil, Susan T.. Treatment Choices Based on OncotypeDx in the Breast Oncology Care Setting. Journal of Cancer Epidemiology. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-510018
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-510018
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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