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Effects of Growth Hormone Administration on Muscle Strength in Men over 50 Years Old
المؤلفون المشاركون
Redorat, R.
Assumpção, R.
Vaisman, M.
Micmacher, E.
Tavares, A. B. W.
Farinatti, P. T. V.
Conceição, F.
Biesek, S.
Veloso, U.
المصدر
International Journal of Endocrinology
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-12-08
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Growth hormone (GH) use has been speculated to improve physical capacity in subjects without GH deficiency (GHD) through stimulation of collagen synthesis in the tendon and skeletal muscle, which leads to better exercise training and increased muscle strength.
In this context, the use of GH in healthy elderly should be an option for increasing muscle strength.
Our aim was to evaluate the effect of GH therapy on muscle strength in healthy men over 50 years old.
Fourteen healthy men aged 50–70 years were evaluated at baseline for body composition and muscle strength (evaluated by leg press and bench press exercises, which focus primarily on quadriceps—lower body part and pectoralis major—upper body part—muscles, resp.).
Subjects were randomised into 2 groups: GH therapy (7 subjects) and placebo (7 subjects) and reevaluated after 6 months of therapy.
Thirteen subjects completed the study (6 subjects in the placebo group and 7 subjects in the GH group).
Subjects of both groups were not different at baseline.
After 6 months of therapy, muscle strength in the bench press responsive muscles did not increase in both groups and showed a statistically significant increase in the leg press responsive muscles in the GH group.
Our study demonstrated an increase in muscle strength in the lower body part after GH therapy in healthy men.
This finding must be considered and tested in frail older populations, whose physical incapacity is primarily caused by proximal muscle weakness.
The trial was registered with NCT01853566.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tavares, A. B. W.& Micmacher, E.& Biesek, S.& Assumpção, R.& Redorat, R.& Veloso, U.…[et al.]. 2013. Effects of Growth Hormone Administration on Muscle Strength in Men over 50 Years Old. International Journal of Endocrinology،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-510073
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tavares, A. B. W.…[et al.]. Effects of Growth Hormone Administration on Muscle Strength in Men over 50 Years Old. International Journal of Endocrinology No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-510073
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tavares, A. B. W.& Micmacher, E.& Biesek, S.& Assumpção, R.& Redorat, R.& Veloso, U.…[et al.]. Effects of Growth Hormone Administration on Muscle Strength in Men over 50 Years Old. International Journal of Endocrinology. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-510073
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-510073
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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