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Antioxidant and Antiproliferative Activities of Leaf Extracts from Plukenetia volubilis Linneo (Euphorbiaceae)
المؤلفون المشاركون
Melo-Silveira, Raniere Fagundes
Fernandes, Júlia Morais
Scortecci, Katia Castanho
Zucolotto, Silvana Maria
Dantas-Santos, Nednaldo
Rocha, Hugo Alexandre Oliveira
Nascimento, Ana Karina Lima
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-09-18
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Plukenetia volubilis Linneo, or Sacha inca, is an oleaginous plant from the Euphorbiaceae family.
The aim of this work was to perform a chemical and biological analysis of different leaf extracts from P.
volubilis such as aqueous extract (AEL), methanol (MEL), ethanol (EEL), chloroform (CEL), and hexane (HEL).
Thin layer chromatography analysis revealed the presence of phenolic compounds, steroids, and/or terpenoídes.
Furthermore, the antioxidant activities were analyzed by in vitro assays and their effects on cell lineages by in vivo assays.
The Total Antioxidant Capacity (TCA) was expressed as equivalent ascorbic acid (EEA/g) and it was observed that the extracts showed values ranging from 59.31 to 97.76 EAA/g.
Furthermore, the DPPH assay values ranged from 62.8% to 88.3%.
The cell viability assay showed that the extracts were able to reduce viability from cancer cells such as HeLa and A549 cells.
The extracts MEL and HEL (250 µg/mL) were able to reduce the proliferation of HeLa cells up to 54.3% and 48.5%, respectively.
The flow cytometer results showed that these extracts induce cell death via the apoptosis pathway.
On the other hand, the extracts HEL and AEL were able to induce cell proliferation of normal fibroblast 3T3 cells.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Nascimento, Ana Karina Lima& Melo-Silveira, Raniere Fagundes& Dantas-Santos, Nednaldo& Fernandes, Júlia Morais& Zucolotto, Silvana Maria& Rocha, Hugo Alexandre Oliveira…[et al.]. 2013. Antioxidant and Antiproliferative Activities of Leaf Extracts from Plukenetia volubilis Linneo (Euphorbiaceae). Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-510716
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Nascimento, Ana Karina Lima…[et al.]. Antioxidant and Antiproliferative Activities of Leaf Extracts from Plukenetia volubilis Linneo (Euphorbiaceae). Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-510716
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Nascimento, Ana Karina Lima& Melo-Silveira, Raniere Fagundes& Dantas-Santos, Nednaldo& Fernandes, Júlia Morais& Zucolotto, Silvana Maria& Rocha, Hugo Alexandre Oliveira…[et al.]. Antioxidant and Antiproliferative Activities of Leaf Extracts from Plukenetia volubilis Linneo (Euphorbiaceae). Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-510716
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-510716
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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