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Vancomycin-Resistant Enterococcus faecium Bacteremia in a Tertiary Care Hospital : Epidemiology, Antimicrobial Susceptibility, and Outcome
المؤلفون المشاركون
Machado, Denise P.
Turra, Eduardo E.
Rosa, Regis Goulart
Schwarzbold, Alexandre V.
Goldani, Luciano Zubaran
dos Santos, Rodrigo Pires
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-03-05
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Vancomycin-resistant Enterococcus faecium (VREF) has emerged as a relevant multidrug-resistant pathogen and potentially lethal etiology of health care associated infections worldwide.
The objective of this retrospective cohort study was to assess factors associated with mortality in patients with VREF bacteremia in a major tertiary referral hospital in Southern Brazil.
All documented cases of bacteremia identified between May 2010 and July 2012 were evaluated.
Cox regression was performed to determine whether the characteristics related to the host or antimicrobial treatment were associated with the all-cause 30-day mortality.
In total, 35 patients with documented VREF bacteremia were identified during the study period.
The median APACHE-II score of the study population was 26 (interquartile range: 10).
The overall 30-day mortality was 65.7%.
All VREF isolates were sensitive to linezolid, daptomycin, and quinupristin-dalfopristin.
Linezolid was the only antimicrobial agent with in vitro activity against VREF that was administered to the cohort.
After multivariate analysis, linezolid treatment (HR, 0.08; 95% CI, 0.02–0.27) and presence of acute kidney injury at the onset of bacteremia (HR, 4.01; 95% CI, 1.62–9.94) were independently associated with mortality.
Presentation with acute kidney injury and lack of treatment with an effective antibiotic poses risk for mortality in patients with VREF bacteremia.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Rosa, Regis Goulart& Schwarzbold, Alexandre V.& dos Santos, Rodrigo Pires& Turra, Eduardo E.& Machado, Denise P.& Goldani, Luciano Zubaran. 2014. Vancomycin-Resistant Enterococcus faecium Bacteremia in a Tertiary Care Hospital : Epidemiology, Antimicrobial Susceptibility, and Outcome. BioMed Research International،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-511447
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Rosa, Regis Goulart…[et al.]. Vancomycin-Resistant Enterococcus faecium Bacteremia in a Tertiary Care Hospital : Epidemiology, Antimicrobial Susceptibility, and Outcome. BioMed Research International No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-511447
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Rosa, Regis Goulart& Schwarzbold, Alexandre V.& dos Santos, Rodrigo Pires& Turra, Eduardo E.& Machado, Denise P.& Goldani, Luciano Zubaran. Vancomycin-Resistant Enterococcus faecium Bacteremia in a Tertiary Care Hospital : Epidemiology, Antimicrobial Susceptibility, and Outcome. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-511447
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-511447
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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