The Current Practice of Screening, Prevention, and Treatment of Androgen-Deprivation-Therapy Induced Osteoporosis in Patients with Prostate Cancer
المؤلفون المشاركون
Lau, Arthur N.
Ioannidis, George
Malik, Kartika
Alamri, Abdulaziz
al-Shamsi, Humaid O.
Papaioannou, Alexandra
Corbett, Tom
Adachi, J. D.
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-04-30
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Introduction.
ADT is used in the management of locally advanced and metastatic disease.
The detrimental effect of ADT on bone density is well documented.
This study assesses care gaps in screening, prevention and treatment of osteoporosis among prostate cancer patients.
Methods.
We conducted a retrospective cohort study for patients diagnosed with non-metastatic prostate cancer on ADT.
Charts from a tertiary oncology center were assessed for utilization of DXA scan, prescription of calcium, vitamin D, calcitonin and bisphosphonates.Bivariate analysis was used to determine the effect of patient characteristics and likelihood for osteoporosis screening.
Results.
149 charts were reviewed, with 3-year mean follow-up.
58.8% of men received a baseline DXA, of which 20.3% had a repeat DXA within their follow-up periods.In all, 28% were appropriately screened and managed for osteoporosis (received repeat DXA, bisphosphonate).
In bivariate analysis, the number of ADT injections which correlate with the duration of androgen suppression was significantly associated with the number of DXA scans.
Conclusions.
Our study found a care gap in the screening, prevention, and treatment of osteoporosis in this population.
Patients receiving the most ADT injections were more likely to be screened.
Our results suggest healthcare providers treating prostate cancer are insufficiently screening and treating this susceptible population.
We suggest baseline measurement of BMD at the initiation of ADT with periodic reassessment during therapy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Shamsi, Humaid O.& Lau, Arthur N.& Malik, Kartika& Alamri, Abdulaziz& Ioannidis, George& Corbett, Tom…[et al.]. 2012. The Current Practice of Screening, Prevention, and Treatment of Androgen-Deprivation-Therapy Induced Osteoporosis in Patients with Prostate Cancer. Journal of Oncology،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-511454
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Shamsi, Humaid O.…[et al.]. The Current Practice of Screening, Prevention, and Treatment of Androgen-Deprivation-Therapy Induced Osteoporosis in Patients with Prostate Cancer. Journal of Oncology No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-511454
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Shamsi, Humaid O.& Lau, Arthur N.& Malik, Kartika& Alamri, Abdulaziz& Ioannidis, George& Corbett, Tom…[et al.]. The Current Practice of Screening, Prevention, and Treatment of Androgen-Deprivation-Therapy Induced Osteoporosis in Patients with Prostate Cancer. Journal of Oncology. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-511454
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-511454
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر