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Measuring Thickness of Middle Ear Mucosa Using MRI and CT Imaging versus Histopathology
المؤلفون المشاركون
Nyc, Mary Ann
Jung, Timothy
Kapoor, Anil
Kim, Sang Gyoon
المصدر
International Journal of Otolaryngology
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-03-08
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objective.
Otitis media (OM) is characterized by increased middle ear effusion and inflammation of middle ear tissue.
In this study, we compared two radiographic methods of analyzing inflammation by measuring mucosal thickness (MT).
Methods.
28 chinchillas were divided into three treatment groups consisting of a vehicle control group and two glucocorticoid groups.
6 underwent treatment by vehicle control, 10 were treated with ciprofloxacin 0.3%/dexamethasone 0.1% (DEX), and 10 received ciprofloxacin 0.2%/hydrocortisone 1% (HC).
96 hrs post-LPS inoculation, chinchillas were euthanized and their temporal bones were removed for analyses.
Results.
MRI scans (F=146.0861, P-value <0.0001) and histology (χ2=40.5267, P-value <0.0001) revealed statistically significant differences in MT measurements among treatment groups, whereas CT imaging did not.
DEX-treated chinchillas exhibited overall significantly smaller MT values.
Conclusion.
Imaging MT was effective for determining severity of inflammation due to OM.
Previous gold standard methods using histopathology compromise tissue integrity by chemical manipulation and dehydration effects.
MRI and CT scanning are viable tools to preserve tissue and examine changes in MT.
In this study, MRI provided more information about internal, soft tissue structures.
In a clinical setting, MRI could be used for diagnosing and tracking severe or chronic OM.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Nyc, Mary Ann& Kim, Sang Gyoon& Kapoor, Anil& Jung, Timothy. 2012. Measuring Thickness of Middle Ear Mucosa Using MRI and CT Imaging versus Histopathology. International Journal of Otolaryngology،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-511777
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Nyc, Mary Ann…[et al.]. Measuring Thickness of Middle Ear Mucosa Using MRI and CT Imaging versus Histopathology. International Journal of Otolaryngology No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-511777
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Nyc, Mary Ann& Kim, Sang Gyoon& Kapoor, Anil& Jung, Timothy. Measuring Thickness of Middle Ear Mucosa Using MRI and CT Imaging versus Histopathology. International Journal of Otolaryngology. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-511777
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-511777
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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