Which Imaging Modality Is Superior for Prediction of Response to Neoadjuvant Chemotherapy in Patients with Triple Negative Breast Cancer?
المؤلفون المشاركون
Appleton, Catherine M.
Gao, Feng
Fisher, Carla S.
Margenthaler, Julie A.
Atkins, Jordan J.
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-02-11
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background and Objectives.
Triple negative breast cancer (TNBC) has been shown to be generally chemosensitive.
We sought to investigate the utility of mammography (MMG), ultrasonography (US), and breast magnetic resonance imaging (MRI) in predicting residual disease following neoadjuvant chemotherapy for TNBC.
Methods.
We identified 148 patients with 151 Stage I–III TNBC treated with neoadjuvant chemotherapy.
Residual tumor size was estimated by MMG, US, and/or MRI prior to surgical intervention and compared to the subsequent pathologic residual tumor size.
Data were compared using chi-squared test.
Results.
Of 151 tumors, 44 (29%) did not have imaging performed prior to surgical treatment.
Thirty-eight (25%) tumors underwent a pathologic complete response (pCR), while 113 (75%) had residual invasive disease.
The imaging modality was accurate to within 1 cm of the final pathologic residual disease in 74 (69%) cases and within 2 cm in 94 (88%) cases.
Groups were similar with regards to patient age, race, tumor size and grade, and clinical stage (P>0.05).
Accuracy to within 1 cm was the highest for US (83%) and the lowest for MMG (56%) (P<0.05).
Conclusions.
Breast US and MRI were more accurate than MMG in predicting residual tumor size following neoadjuvant chemotherapy in patients with TNBC.
None of the imaging modalities were predictive of a pCR.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Atkins, Jordan J.& Appleton, Catherine M.& Fisher, Carla S.& Gao, Feng& Margenthaler, Julie A.. 2013. Which Imaging Modality Is Superior for Prediction of Response to Neoadjuvant Chemotherapy in Patients with Triple Negative Breast Cancer?. Journal of Oncology،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-511987
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Atkins, Jordan J.…[et al.]. Which Imaging Modality Is Superior for Prediction of Response to Neoadjuvant Chemotherapy in Patients with Triple Negative Breast Cancer?. Journal of Oncology No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-511987
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Atkins, Jordan J.& Appleton, Catherine M.& Fisher, Carla S.& Gao, Feng& Margenthaler, Julie A.. Which Imaging Modality Is Superior for Prediction of Response to Neoadjuvant Chemotherapy in Patients with Triple Negative Breast Cancer?. Journal of Oncology. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-511987
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-511987
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر