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Histopathological Correlation of Atypical (C3) and Suspicious (C4) Categories in Fine Needle Aspiration Cytology of the Breast
المؤلفون المشاركون
Kumar, Awanindra
Singh, Sompal
Ghosh, Soumyesh
Goyal, Prashant
Sehgal, Shelly
Aggarwal, Deepti
Shukla, Pritesh
Gupta, Ruchika
المصدر
International Journal of Breast Cancer
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-09-23
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Introduction.
According to the National Cancer Institute (NCI) guidelines in 1996, breast lesions are categorized as C1 to C5 on fine needle aspiration (FNA) cytology.
Very few studies are available in the English literature analyzing histopathology outcome of C3 (atypical, probably benign) and C4 (suspicious, probably malignant) lesions.
Our study aims to correlate FNA cytology of breast lump diagnosed as C3 and C4 lesion with histopathological examination.
Methods.
During a period of 2 years, 59 cases of C3 and 26 cases of C4 were retrieved from total 1093 cases of breast FNA.
All the cases were reviewed by two cytopathologists independently.
The final 24 cases of C3 and 16 cases of C4 categories were correlated with histopathological diagnosis.
Result.
Among C3 category, 37.5% revealed malignant findings, whereas of C4 category, 87.5% were malignant on histopathology.
This difference was statistically significant (P=0.0017).
Sensitivity, specificity, positive predictive values, and negative predictive value of C4 category in diagnosing breast malignancy were 60.8%, 88.2%, 87.5%, and 62.5%, respectively.
Conclusion.
Although FNAC is simple, safe, cost-effective and accurate method for diagnosis of breast masses, one must be aware of its limitations particularly in C3 and C4 categories.
Also, since both these categories carry different probabilities of malignancy and thus different management, we therefore, support maintaining C3 and C4 categories.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Goyal, Prashant& Sehgal, Shelly& Ghosh, Soumyesh& Aggarwal, Deepti& Shukla, Pritesh& Kumar, Awanindra…[et al.]. 2013. Histopathological Correlation of Atypical (C3) and Suspicious (C4) Categories in Fine Needle Aspiration Cytology of the Breast. International Journal of Breast Cancer،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-512054
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Goyal, Prashant…[et al.]. Histopathological Correlation of Atypical (C3) and Suspicious (C4) Categories in Fine Needle Aspiration Cytology of the Breast. International Journal of Breast Cancer No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-512054
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Goyal, Prashant& Sehgal, Shelly& Ghosh, Soumyesh& Aggarwal, Deepti& Shukla, Pritesh& Kumar, Awanindra…[et al.]. Histopathological Correlation of Atypical (C3) and Suspicious (C4) Categories in Fine Needle Aspiration Cytology of the Breast. International Journal of Breast Cancer. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-512054
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-512054
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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