Enhanced Antitumoral Activity of Extracts Derived from Cultured Udotea flabellum (Chlorophyta)
المؤلفون المشاركون
Moo-Puc, Rosa
Freile-Pelegrin, Yolanda
Robledo, Daniel
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-07-21
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Very few studies have been performed to evaluate the effect of culture conditions on the production or activity of active metabolites in algae.
Previous studies suggest that the synthesis of bioactive compounds is strongly influenced by irradiance level.
To investigate whether the antiproliferative activity of Udotea flabellum extracts is modified after cultivation, this green alga was cultured under four photon flux densities (PFD) for 30 days.
After 10, 20, and 30 days, algae were extracted with dichloromethane: methanol and screened for antiproliferative activity against four human cancer cell lines (laryngeal—Hep-2, cervix—HeLa, cervix squamous—SiHa and nasopharynx—KB) by SRB assay.
Lipid and phenol content were evaluated by standardized methods on algae organic extracts.
After 10 days of cultivation, organic U.
flabellum extracts showed a significant increase in antiproliferative activity on Hela and SiHa cells when compared to noncultured algae extracts.
Extracts obtained after 10 and 20 days of culture were active on KB and Hep-2 cells.
Total phenol and polyunsaturated fatty acid content in organic extracts changed with cultivation time but not by irradiance treatment.
Extracts from U.
flabellum obtained after 10 and 20 days of culture have been selected for fractionation and isolation of active compounds.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Moo-Puc, Rosa& Robledo, Daniel& Freile-Pelegrin, Yolanda. 2011. Enhanced Antitumoral Activity of Extracts Derived from Cultured Udotea flabellum (Chlorophyta). Evidence-Based Complementary and Alternative Medicine،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-512263
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Moo-Puc, Rosa…[et al.]. Enhanced Antitumoral Activity of Extracts Derived from Cultured Udotea flabellum (Chlorophyta). Evidence-Based Complementary and Alternative Medicine No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-512263
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Moo-Puc, Rosa& Robledo, Daniel& Freile-Pelegrin, Yolanda. Enhanced Antitumoral Activity of Extracts Derived from Cultured Udotea flabellum (Chlorophyta). Evidence-Based Complementary and Alternative Medicine. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-512263
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-512263
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر