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Analysis of Inflammatory Mediators in Type 2 Diabetes Patients
المؤلفون المشاركون
al-Abri, Said
al-Ghafri, Saif
al-Marhoobi, Safia
al-Shukaili, Ahmed
al-Lawati, Jawad
al-Maskari, Masoud
المصدر
International Journal of Endocrinology
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-05-20
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
The main aim of this study is to assess the inflammatory markers in type 2 diabetes mellitus (T2DM) by measuring some cytokines concentrations and lymphocytes subset and correlate them with other laboratory investigations.
Fifty-seven patients with type-2 diabetes and 30 healthy volunteers were enrolled in this study.
Data for the C-reactive protein (CRP), haemoglobin, HbA1c, and autoantibody levels were obtained from the patients files.
The cytokine concentrations were measured in patient’s serum using commercially available ELISA assays.
Lymphocytes subsets were measured by flow cytometric methods.
The levels of IL-1β, IL-6, IL-15, and TNF-α were found to be decreased in T2DM patients, whereas the levels of IL-10, IFN-γ, and caspase-1 were increased, compared to normal controls.
T2DM patients with hypertension show significantly decreased levels of IL-1β and caspase-1 compared to patients without hypertension.
No significant differences in lymphocytes subset between cases and normal control were observed.
Significant correlations were found between HbA1c and IL-6; body mass index (BMI) was significantly correlated with CRP, TNF-α, and phosphate; the weight (Wt) was associated with CRP and IFN-γ.
In conclusion, an alteration in the function of the immune system was observed in T2DM patient.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Shukaili, Ahmed& al-Ghafri, Saif& al-Marhoobi, Safia& al-Abri, Said& al-Lawati, Jawad& al-Maskari, Masoud. 2013. Analysis of Inflammatory Mediators in Type 2 Diabetes Patients. International Journal of Endocrinology،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-512979
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Shukaili, Ahmed…[et al.]. Analysis of Inflammatory Mediators in Type 2 Diabetes Patients. International Journal of Endocrinology No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-512979
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Shukaili, Ahmed& al-Ghafri, Saif& al-Marhoobi, Safia& al-Abri, Said& al-Lawati, Jawad& al-Maskari, Masoud. Analysis of Inflammatory Mediators in Type 2 Diabetes Patients. International Journal of Endocrinology. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-512979
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-512979
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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