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Antineutrophil Cytoplasmic Antibody Frequency in Chronic Hepatitis B Patients
المؤلفون المشاركون
Sokmen, Hacı Mehmet
Kahraman, Resul
Altunoz, Mustafa Erhan
Ozdil, Kamil
Sahin, Abdurrahman
Ozbakır, Fatma
Calhan, Turan
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-08-05
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Background.
Chronic hepatitis B (CHB) is a viral disease, common across the world, and associated with several extraintestinal manifestations including vasculitis.
Antineutrophil cytoplasmic antibodies (ANCAs) are sensitive and specific markers for vasculitides.
There is limited data available in the literature on whether ANCA formation is stimulated by CHB infection.
In the present study we aimed to identify the frequency of ANCA in CHB patients.
Methods.
A total of 174 subjects were included in the study (87 CHB patients, 87 control subjects).
Perinuclear-ANCA (P-ANCA), cytoplasmic-ANCA (C-ANCA), myeloperoxidase ANCA (MPO-ANCA), and proteinase 3-ANCA (PR3-ANCA) were studied.
IFA was used for P-ANCA and C-ANCA assays, and ELISA was used for MPO-ANCA and PR3-ANCA assays.
Results.
ANCA positivity was high in both groups (31% in the CHB group and 26% among controls).
There were no significant differences between the groups for P-ANCA and MPO-ANCA (P = 0.6 and P = 0.6, resp.).
Frequency of borderline positive C-ANCA and all positive PR3-ANCA (positive + borderline positive) was significantly higher in the CHB group (P = 0.009 and P = 0.005, resp.).
Conclusions.
In the present study, the frequency of ANCA was high in both groups.
The CHB group had a relatively higher frequency of ANCA positivity compared to controls.
Borderline positive C-ANCA and positive PR3-ANCA were significantly higher in the CHB group.
These results suggest that ANCA may have a high prevalence in Turkey.
Patients with CHB should be evaluated particularly for C-ANCA and PR3-ANCA in the presence of vasculitic complaints and lesions.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Calhan, Turan& Sahin, Abdurrahman& Kahraman, Resul& Altunoz, Mustafa Erhan& Ozbakır, Fatma& Ozdil, Kamil…[et al.]. 2014. Antineutrophil Cytoplasmic Antibody Frequency in Chronic Hepatitis B Patients. Disease Markers،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-513372
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Calhan, Turan…[et al.]. Antineutrophil Cytoplasmic Antibody Frequency in Chronic Hepatitis B Patients. Disease Markers No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-513372
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Calhan, Turan& Sahin, Abdurrahman& Kahraman, Resul& Altunoz, Mustafa Erhan& Ozbakır, Fatma& Ozdil, Kamil…[et al.]. Antineutrophil Cytoplasmic Antibody Frequency in Chronic Hepatitis B Patients. Disease Markers. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-513372
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-513372
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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