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Malignancy Risk Assessment in Patients with Thyroid Nodules Using Classification and Regression Trees
المؤلفون المشاركون
Noshad, Sina
Mirouliaei, Mehrdad
Khajeh, Elias
Binesh, Fariba
Taghipour Zahir, Shokouh
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-09-11
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Purpose.
We sought to investigate the utility of classification and regression trees (CART) classifier to differentiate benign from malignant nodules in patients referred for thyroid surgery.
Methods.
Clinical and demographic data of 271 patients referred to the Sadoughi Hospital during 2006–2011 were collected.
In a two-step approach, a CART classifier was employed to differentiate patients with a high versus low risk of thyroid malignancy.
The first step served as the screening procedure and was tailored to produce as few false negatives as possible.
The second step identified those with the lowest risk of malignancy, chosen from a high risk population.
Sensitivity, specificity, positive and negative predictive values (PPV and NPV) of the optimal tree were calculated.
Results.
In the first step, age, sex, and nodule size contributed to the optimal tree.
Ultrasonographic features were employed in the second step with hypoechogenicity and/or microcalcifications yielding the highest discriminatory ability.
The combined tree produced a sensitivity and specificity of 80.0% (95% CI: 29.9–98.9) and 94.1% (95% CI: 78.9–99.0), respectively.
NPV and PPV were 66.7% (41.1–85.6) and 97.0% (82.5–99.8), respectively.
Conclusion.
CART classifier reliably identifies patients with a low risk of malignancy who can avoid unnecessary surgery.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Taghipour Zahir, Shokouh& Binesh, Fariba& Mirouliaei, Mehrdad& Khajeh, Elias& Noshad, Sina. 2013. Malignancy Risk Assessment in Patients with Thyroid Nodules Using Classification and Regression Trees. Journal of Thyroid Research،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-513538
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Taghipour Zahir, Shokouh…[et al.]. Malignancy Risk Assessment in Patients with Thyroid Nodules Using Classification and Regression Trees. Journal of Thyroid Research No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-513538
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Taghipour Zahir, Shokouh& Binesh, Fariba& Mirouliaei, Mehrdad& Khajeh, Elias& Noshad, Sina. Malignancy Risk Assessment in Patients with Thyroid Nodules Using Classification and Regression Trees. Journal of Thyroid Research. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-513538
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-513538
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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