The Effects of Continuous Blood Purification for SIRSMODS Patients : A Systematic Review and Meta-Analysis of Randomized Controlled Trials
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-09-26
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Background.
Continuous veno-venous hemofiltration (CVVH) has aroused great concern in recent years because its effect on clearing inflammatory mediators and its mechanism of clinical effects in the treatment of critical illness has also become a research direction.
Objective.
To evaluate the efficacy of continuous blood purification for systemic inflammatory response syndrome (SIRS)/multiple organ dysfunction syndrome (MODS) patients.
Methods.
A systematic review of the literature was undertaken to assess randomized controlled trials on CVVH.
Results.
11 RCTs involving a total of 414 patients were included.
Compared with the control group, CVVH for SIRS/MODS patients has several advantages including better effects on clearing the plasma inflammatory mediators IL-6 [SMD3d=−0.45, 95%CI, (−0.83, −0.07), SMD7d=−1.07, 95%CI, (−1.52, −0.62)], on plasma TNF-alfa [SMD3d=−0.87, 95%CI, (−1.69, −0.04), SMD7d=−1.42, 95%CI, (−2.49, −0.35)], lower white blood cell (WBC) count [MD=2.61, 95%CI, (1.49, 3.73)], shorter hospital stays [MD=−7.21 days, 95%CI, (−10.68, −3.74)] and better stability of hemodynamics.
However, there is no significant difference in the mortality rate [MODS:RR=0.62, 95%CI, (0.38, 1.01), SIRS:RR=0.75, 95%CI, (0.57, 1.08)].
Conclusions.
The study showed that CVVH was able to eliminate inflammatory mediators (TNF-alfa, IL-6) in plasma effectively, lower WBC count and shorter hospital stays than conventional therapeutic measures.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
2012. The Effects of Continuous Blood Purification for SIRSMODS Patients : A Systematic Review and Meta-Analysis of Randomized Controlled Trials. ISRN Hematology،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-513840
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
The Effects of Continuous Blood Purification for SIRSMODS Patients : A Systematic Review and Meta-Analysis of Randomized Controlled Trials. ISRN Hematology No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-513840
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
The Effects of Continuous Blood Purification for SIRSMODS Patients : A Systematic Review and Meta-Analysis of Randomized Controlled Trials. ISRN Hematology. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-513840
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-513840
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر