Alzheimer's Disease Promotion by Obesity : Induced Mechanisms—Molecular Links and Perspectives
المؤلفون المشاركون
Canitano, Nicoletta
Businaro, Rita
Fuso, Andrea
Ricci, Serafino
Ippoliti, Flora
المصدر
Current Gerontology and Geriatrics Research
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-06-04
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
The incidence of AD is increasing in parallel with the increase in life expectancy.
At the same time the prevalence of metabolic syndrome and obesity is reaching epidemic proportions in western populations.
Stress is one of the major inducers of visceral fat and obesity development, underlying accelerated aging processes.
Adipose tissue is at present considered as an active endocrine organ, producing important mediators involved in metabolism regulation as well as in inflammatory mechanisms.
Insulin and leptin resistance has been related to the dysregulation of energy balance and to the induction of a chronic inflammatory status which have been recognized as important cofactors in cognitive impairment and AD initiation and progression.
The aim of this paper is to disclose the correlation between the onset and progression of AD and the stress-induced changes in lifestyle, leading to overnutrition and reduced physical activity, ending with metabolic syndrome and obesity.
The involved molecular mechanisms will be briefly discussed, and advisable guide lines for the prevention of AD through lifestyle modifications will be proposed.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Businaro, Rita& Ippoliti, Flora& Ricci, Serafino& Canitano, Nicoletta& Fuso, Andrea. 2012. Alzheimer's Disease Promotion by Obesity : Induced Mechanisms—Molecular Links and Perspectives. Current Gerontology and Geriatrics Research،Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-513845
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Businaro, Rita…[et al.]. Alzheimer's Disease Promotion by Obesity : Induced Mechanisms—Molecular Links and Perspectives. Current Gerontology and Geriatrics Research No. 2012 (2012), pp.1-13.
https://search.emarefa.net/detail/BIM-513845
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Businaro, Rita& Ippoliti, Flora& Ricci, Serafino& Canitano, Nicoletta& Fuso, Andrea. Alzheimer's Disease Promotion by Obesity : Induced Mechanisms—Molecular Links and Perspectives. Current Gerontology and Geriatrics Research. 2012. Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-513845
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-513845
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر