Trial of tramadol plus gabapentin for opioid detoxification
المؤلفون المشاركون
Ziaaddini, Hasan
Ziaaddini, Ahmad
Asghari, Nada
Islami, Mahin
Nakhaee, Nozar
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 17، العدد 1 (31 يناير/كانون الثاني 2015)، ص ص. 1-5، 5ص.
الناشر
تاريخ النشر
2015-01-31
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Background : Substance abuse or drug addiction is one of the most important health issues in every society, which can lead to physical and mental problems.
Objectives : This study aimed to compare the efficacy of tramadol plus gabapentin versus methadone use in the treatment of opiate withdrawal.
Patients and Methods : Consenting male subjects who fulfilled the DSM-4 criteria for opiate dependence syndrome (opium, residue, and heroin) were randomly assigned in two groups to receive tramadol plus gabapentin or methadone.
Assessment tools were Adjective Rating Scale for Withdrawal (ARSW), Clinical Opiate Withdrawal Scale (COWS) and Visual Analogue craving Scale (VAS).
Fifty-nine subjects were enrolled and evaluated on days 1, 2, 3, 4, 6, and 8 during their 10 days of admission.
Twenty-nine participants received methadone and the other 30 received tramadol plus gabapentin for their treatment.
Results : Mean (SD) age of the patients in methadone group and tramadol plus gabapentin group were 33.9 (7.1) and 32.4.
(8.1), respectively (P = 0.462).
The overall ARSW (P value = 0.263) and COWS (P = 0.862) scores between the two groups were comparable.
The differences in the VAS score for craving between the two groups was marginally significant (P = 0.057).
The highest VAS score was at the third day of admission in both groups and it was generally higher in methadone group.
Conclusions : The severity of withdrawal syndrome in two groups was not significantly different.
The craving was higher in the group receiving methadone from the second day of admission even though the usage amount was higher in the tramadol plus gabapentin group.
The findings of this study suggest that the combination of tramadol plus gabapentin is an efficient method for opioid detoxification.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ziaaddini, Hasan& Ziaaddini, Ahmad& Asghari, Nada& Nakhaee, Nozar& Islami, Mahin. 2015. Trial of tramadol plus gabapentin for opioid detoxification. Iranian Red Crescent Medical Journal،Vol. 17, no. 1, pp.1-5.
https://search.emarefa.net/detail/BIM-519742
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ziaaddini, Hasan…[et al.]. Trial of tramadol plus gabapentin for opioid detoxification. Iranian Red Crescent Medical Journal Vol. 17, no. 1 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-519742
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ziaaddini, Hasan& Ziaaddini, Ahmad& Asghari, Nada& Nakhaee, Nozar& Islami, Mahin. Trial of tramadol plus gabapentin for opioid detoxification. Iranian Red Crescent Medical Journal. 2015. Vol. 17, no. 1, pp.1-5.
https://search.emarefa.net/detail/BIM-519742
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 4-5
رقم السجل
BIM-519742
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر