Effect of androgenic anabolic steroide dianabol in some haematological and immunological criteria for male albino rats

الملخص EN

The present study was performed to examine effect of androgenic anabolic steroide dianabol in some haematological and immunological criteria for male Albino rat.

The animals were divided in to four groups (6 animals for each group) first, second and third treatment groups gives orally suspended dianabol 10,20 and 40 mg / kg / day respectively, while the fourth group (control) gives physiological normal saline (0.85 %), and all groups primed for 8 weeks.

The results showed that significant increase`(P < 0.05) in RBC count, platelets count, Hb, p.c.v and percentage of lymphocytes in treatments groups compared with control, while the WBCs count show significant decrease (p < 0.05) in percentages of granulocytes and monocytes, furthermore, the results refer that significant decrease (p < 0.05) in concentrations of GM-CSF and total protein in treated groups compared with control group.