Biochemical changes of liver that infected with entamoeba histolytica in white rats

الملخص EN

This study was carried out in the animal house of the Science College, Babylon University for the period from of October 2012 till February 2013.

This study included, 20 white Swiss Rattus rattus ages between 3-4 months, and weights between 250-300 gm.

Animals were divided into five groups (2, 4 , 8 ,12) weeks and the fifth group consider as control group each group included (four males).

Four groups were infected with suspension E.

histolytica that bring from stools patients attending to the Al- Hilla Hospital Laboratory, every rat gives about 103 cysts per mililiter of E.

histolytica through oral administration.

And the fifth group treated orally with distilled water.

The rats liver were studied functionally by measuring the level of enzymes AST, ALT, ALP.

The tests of liver enzymes, showed that the level of the enzyme AST, ALT, ALP having significant increased (P < 0.05) in the male rats treated E.

histolytica suspension compared to control group.

The infection with E.

histolytica established histological changes in the organs especially the liver as apoptosis death of cells as well as changes in biochemical parameters (ALP, AST, ALT).