Prevalence of vitamin D deficiency in Egyptian rheumatoid Arthritis patients : correlation with disease activity, functional disability, and bone mineral density
المؤلفون المشاركون
Allam, Nashwa T.
al-Wakid, Muhammad M.
al-Abd, Dina M.
Dirgham, Daliyah A.
المصدر
Egyptian Rheumatology and Rehabilitation
العدد
المجلد 41، العدد 3 (30 سبتمبر/أيلول 2014)، ص ص. 92-97، 6ص.
الناشر
الجمعية المصرية للروماتيزم و التأهيل
تاريخ النشر
2014-09-30
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الموضوعات
الملخص EN
Aim of Work : To detect the prevalence of 25-hydroxyvitamin D3 [25(OH)D3] deficiency in rheumatoid arthritis (RA) patients and its correlation with disease activity, functional disability and bone mineral density (BMD).
Patients and Methods : Cross-sectional case control study included 104 RA patients and 60 matched controls.
All patients were subjected to full history taking, clinical examination and routine laboratory investigations in addition to measurements of serum 25(OH)D3.
Disease activity was assessed by 28-Disease Activity Score (DAS-28) with three variables ; tender and swollen 28-joints (T-28 and S-28) and erythrocyte sedimentation rate (ESR).
Functional disability was assessed by Modified Health Assessment Questionnaire (M-HAQ).
BMD was measured by dual energy x-ray absorptiometry.
Results : 25(OH)D3 deficiency was similar in both RA patients and controls (99.1 % versus 100 %).
Although, the mean serum 25(OH)D3 level was less among RA patients than among controls but there was no statistical significant difference (5.98 ± 6.8 nmol / l versus 8.4 ± 9.6 nmol / l, p = 0.06).
There were statistically significant correlations between 25(OH)D3 and body weight (r = −0.256, p < 0.009), T-28 (r = −0.559, p < 0.001), S-28 (r = −0.631, p < 0.001), DAS-28 (p < 0.001), M-HAQ (p < 0.001) scores, ESR (r = −0.39, p < 0.001) and hemoglobin (r = 0.28, p = 0.004).
No significant correlation was found between 25(OH)D3 level and BMD or drug intake.
Conclusion : Although the prevalence of 25(OH)D3 deficiency is similar in both RA patients and controls but its deficiency is significantly correlated with increased disease activity and disability but not with BMD.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Allam, Nashwa T.& al-Wakid, Muhammad M.& al-Abd, Dina M.& Dirgham, Daliyah A.. 2014. Prevalence of vitamin D deficiency in Egyptian rheumatoid Arthritis patients : correlation with disease activity, functional disability, and bone mineral density. Egyptian Rheumatology and Rehabilitation،Vol. 41, no. 3, pp.92-97.
https://search.emarefa.net/detail/BIM-520219
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Allam, Nashwa T.…[et al.]. Prevalence of vitamin D deficiency in Egyptian rheumatoid Arthritis patients : correlation with disease activity, functional disability, and bone mineral density. Egyptian Rheumatology and Rehabilitation Vol. 41, no. 3 (2014), pp.92-97.
https://search.emarefa.net/detail/BIM-520219
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Allam, Nashwa T.& al-Wakid, Muhammad M.& al-Abd, Dina M.& Dirgham, Daliyah A.. Prevalence of vitamin D deficiency in Egyptian rheumatoid Arthritis patients : correlation with disease activity, functional disability, and bone mineral density. Egyptian Rheumatology and Rehabilitation. 2014. Vol. 41, no. 3, pp.92-97.
https://search.emarefa.net/detail/BIM-520219
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 96-97
رقم السجل
BIM-520219
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر