Serum leptin, Insulin and parathyroid hormone levels in chronic renal failure patients
العناوين الأخرى
مستوى اللبتن و الأنسولين و الباراثورمون في مرضى الفشل الكلوي المزمن
المؤلفون المشاركون
Farraj, Mahmud Kamil
al-Shadhili, Ashraf Anwar
Bakhit, Madihah Yunus
Subuh, Muhammad Abbas
Halim, Rasha Rashad
al-Jundi, Salwa Salah
المصدر
العدد
المجلد 29، العدد 1 (31 يناير/كانون الثاني 2005)، ص ص. 31-44، 14ص.
الناشر
تاريخ النشر
2005-01-31
دولة النشر
مصر
عدد الصفحات
14
التخصصات الرئيسية
الموضوعات
الملخص EN
Chronic renal failure patients whether they are treated with hemodialysis or on conservative treatment frequently suffer uremic anorexia and malnutrition, which is associated with increased morbidity and mortality.
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In this study we have measured serum leptin, serum insulin and parathyroid hormone in addition to routine kidney function tests, serum glucose, total protein, albumin, lipogram, total serum calcium and inorganic phosphorus.
This study was conducted on forty five male patients with chronic renal failure and ten healthy male subjects as control group (Group I).
According to management of chronic renal failure the patients were divided into two groups: 22 patients on conservative treatment (Group II) and23 patients on hemodialysis (Group III).
Serum levels of both leptin and insulin revealed significant elevation in patient groups (either on conservative or on hemodialysis) compared to controls, also in hemodialysis group compared to group on conservative treatment.
Serum level of intact parathyroid hormone, also showed significant elevation in groups II and III compared to controls with no difference in comparing group III versus group II.
Correlation study in whole patients group revealed significant negative correlations between creatinine clearance with both leptin and insulin.
Also significant positive correlations were found between leptin and insulin and between leptin and intact parathyroid hormone (iPTH).
Anorexia was found in both patient groups II and III (90.9% and 91.3% respectively).
In conclusion: Chronic renal failure patients have hyperleptinemia and hyperinsulinemia and there are important interactions between leptin and insulin in which each hormone may be involved in regulating the function of the other.
Excess parathyroid hormone may play a role in the pathogenesis of both hyperleptinemia and hyperinsulinemia.
Hyperleptinemia may be an important contributing factor for uremic anorexia.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Shadhili, Ashraf Anwar& Bakhit, Madihah Yunus& Farraj, Mahmud Kamil& al-Jundi, Salwa Salah& Halim, Rasha Rashad& Subuh, Muhammad Abbas. 2005. Serum leptin, Insulin and parathyroid hormone levels in chronic renal failure patients. Assiut Medical Journal،Vol. 29, no. 1, pp.31-44.
https://search.emarefa.net/detail/BIM-52123
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Farraj, Mahmud Kamil…[et al.]. Serum leptin, Insulin and parathyroid hormone levels in chronic renal failure patients. Assiut Medical Journal Vol. 29, no. 1(Jan. 2005), pp.31-44.
https://search.emarefa.net/detail/BIM-52123
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Shadhili, Ashraf Anwar& Bakhit, Madihah Yunus& Farraj, Mahmud Kamil& al-Jundi, Salwa Salah& Halim, Rasha Rashad& Subuh, Muhammad Abbas. Serum leptin, Insulin and parathyroid hormone levels in chronic renal failure patients. Assiut Medical Journal. 2005. Vol. 29, no. 1, pp.31-44.
https://search.emarefa.net/detail/BIM-52123
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 42-44
رقم السجل
BIM-52123
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر