The immunohistochemical expression of vascular endothelial growth factor in gastrointestinal stromal tumor : a clinicopathological study
المؤلف
المصدر
Journal of the Faculty of Medicine Baghdad
العدد
المجلد 56، العدد 3 (30 سبتمبر/أيلول 2014)، ص ص. 301-304، 4ص.
الناشر
تاريخ النشر
2014-09-30
دولة النشر
العراق
عدد الصفحات
4
التخصصات الرئيسية
الموضوعات
الملخص EN
Background : Gastrointestinal Stromal Tumors (GISTs), although are rare, are the most common mesenchymal tumors of the digestive system.
Vascular endothelial growth factor (VEGF) is associated with the malignant potential of several types of carcinomas.
Objectives : to evaluate the expression of VEGF in GIST and its correlation with different clinic-pathologic parameters and risk categories.
Patients, material, and methods : This is a retrospective study including thirty two randomly selected cases of GISTs collected from the pathology laboratory of the gastroenterology and hepatology teaching hospital and from private laboratories from the period January 2010 to December 2013.
VEGF immunohistochemical marker was applied to the tumor tissue sections to evaluate its expression and to correlate it with other parameters.
Results : The mean age of the patient was 42.5 years with a female to male ratio of 1.3 : 1.
The stomach was the most common site for the tumor.
VEGF was expressed in 12 (37.5 %) cases.
There was a significant statistical correlation between overexpression of VEGF and the patients' gender and the primary tumor site.
There was no significant statistical correlation between VEGF overexpression and age of the patients, size of the tumor, mitotic index, and risk of malignant potential categories.
Conclusion : There is a significant statistical correlation between VEGF expression and both gender of the patients, and the primary site of GIST.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Khafaji, Khitam R.. 2014. The immunohistochemical expression of vascular endothelial growth factor in gastrointestinal stromal tumor : a clinicopathological study. Journal of the Faculty of Medicine Baghdad،Vol. 56, no. 3, pp.301-304.
https://search.emarefa.net/detail/BIM-526805
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Khafaji, Khitam R.. The immunohistochemical expression of vascular endothelial growth factor in gastrointestinal stromal tumor : a clinicopathological study. Journal of the Faculty of Medicine Baghdad Vol. 58, no. 3 (2014), pp.301-304.
https://search.emarefa.net/detail/BIM-526805
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Khafaji, Khitam R.. The immunohistochemical expression of vascular endothelial growth factor in gastrointestinal stromal tumor : a clinicopathological study. Journal of the Faculty of Medicine Baghdad. 2014. Vol. 56, no. 3, pp.301-304.
https://search.emarefa.net/detail/BIM-526805
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 304
رقم السجل
BIM-526805
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر