Inflammatory markers mediated diabetic nephropathy in patients with type 1 and type 2 diabetes mellitus
المؤلفون المشاركون
Kamil, Layth Abd al-Ilah
Salih, Madha M. Sheet
Dhamad, Ghurub D.
المصدر
Journal of the Faculty of Medicine Baghdad
العدد
المجلد 56، العدد 4 (31 ديسمبر/كانون الأول 2014)، ص ص. 401-404، 4ص.
الناشر
تاريخ النشر
2014-12-31
دولة النشر
العراق
عدد الصفحات
4
التخصصات الرئيسية
الموضوعات
الملخص EN
Background : Diabetic nephropathy (DN) represents the most common cause of end stage renal disease (ESRD) worldwide.
Diabetic nephropathy occurs as a result of an interaction between hemodynamic and metabolic factors, however recent evidence shows an increase growing support for the notion that inflammation plays a key role in the pathogenesis of diabetic nephropathy.
Objectives : To speculate the role of IL-18 and TNF-α proinflammatory cytokines in the initiation and development of diabetic nephropathy in T1DM and T2DM.
Materials and methods : Eighty seven T1DM and T2DM patients with or without DN were enrolled.
IL-18 and TNF-α cytokines were measured by solid phase immunosorbent assays.
Materials and methods : Eighty seven T1DM and T2DM patients with or without DN were enrolled.
IL-18 and TNF-α cytokines were measured by solid phase immunosorbent assays.
Results : IL-18 had increased significantly in patients with DN compared to those without DN in T1DM and T2DM patients whereas TNF-α had exhibited a significant elevation among patients with DN compared to those without DN in T2DM but not T1DM.
Conclusion : IL-18 is suggested to play a crucial role in the initiation, development, and progression of DN in T1DM and T2DM patients whereas TNF-α is playing a similar role but only in T1DM patients with DN.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Salih, Madha M. Sheet& Dhamad, Ghurub D.& Kamil, Layth Abd al-Ilah. 2014. Inflammatory markers mediated diabetic nephropathy in patients with type 1 and type 2 diabetes mellitus. Journal of the Faculty of Medicine Baghdad،Vol. 56, no. 4, pp.401-404.
https://search.emarefa.net/detail/BIM-533384
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Salih, Madha M. Sheet…[et al.]. Inflammatory markers mediated diabetic nephropathy in patients with type 1 and type 2 diabetes mellitus. Journal of the Faculty of Medicine Baghdad Vol. 59, no. 4 (2014), pp.401-404.
https://search.emarefa.net/detail/BIM-533384
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Salih, Madha M. Sheet& Dhamad, Ghurub D.& Kamil, Layth Abd al-Ilah. Inflammatory markers mediated diabetic nephropathy in patients with type 1 and type 2 diabetes mellitus. Journal of the Faculty of Medicine Baghdad. 2014. Vol. 56, no. 4, pp.401-404.
https://search.emarefa.net/detail/BIM-533384
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 403-404
رقم السجل
BIM-533384
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر