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Inflammatory markers mediated diabetic nephropathy in patients with type 1 and type 2 diabetes mellitus
المؤلفون المشاركون
Kamil, Layth Abd al-Ilah
Salih, Madha M. Sheet
Dhamad, Ghurub D.
المصدر
Journal of the Faculty of Medicine Baghdad
العدد
المجلد 56، العدد 4 (31 ديسمبر/كانون الأول 2014)، ص ص. 401-404، 4ص.
الناشر
تاريخ النشر
2014-12-31
دولة النشر
العراق
عدد الصفحات
4
التخصصات الرئيسية
الموضوعات
الملخص EN
Background : Diabetic nephropathy (DN) represents the most common cause of end stage renal disease (ESRD) worldwide.
Diabetic nephropathy occurs as a result of an interaction between hemodynamic and metabolic factors, however recent evidence shows an increase growing support for the notion that inflammation plays a key role in the pathogenesis of diabetic nephropathy.
Objectives : To speculate the role of IL-18 and TNF-α proinflammatory cytokines in the initiation and development of diabetic nephropathy in T1DM and T2DM.
Materials and methods : Eighty seven T1DM and T2DM patients with or without DN were enrolled.
IL-18 and TNF-α cytokines were measured by solid phase immunosorbent assays.
Materials and methods : Eighty seven T1DM and T2DM patients with or without DN were enrolled.
IL-18 and TNF-α cytokines were measured by solid phase immunosorbent assays.
Results : IL-18 had increased significantly in patients with DN compared to those without DN in T1DM and T2DM patients whereas TNF-α had exhibited a significant elevation among patients with DN compared to those without DN in T2DM but not T1DM.
Conclusion : IL-18 is suggested to play a crucial role in the initiation, development, and progression of DN in T1DM and T2DM patients whereas TNF-α is playing a similar role but only in T1DM patients with DN.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Salih, Madha M. Sheet& Dhamad, Ghurub D.& Kamil, Layth Abd al-Ilah. 2014. Inflammatory markers mediated diabetic nephropathy in patients with type 1 and type 2 diabetes mellitus. Journal of the Faculty of Medicine Baghdad،Vol. 56, no. 4, pp.401-404.
https://search.emarefa.net/detail/BIM-533384
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Salih, Madha M. Sheet…[et al.]. Inflammatory markers mediated diabetic nephropathy in patients with type 1 and type 2 diabetes mellitus. Journal of the Faculty of Medicine Baghdad Vol. 59, no. 4 (2014), pp.401-404.
https://search.emarefa.net/detail/BIM-533384
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Salih, Madha M. Sheet& Dhamad, Ghurub D.& Kamil, Layth Abd al-Ilah. Inflammatory markers mediated diabetic nephropathy in patients with type 1 and type 2 diabetes mellitus. Journal of the Faculty of Medicine Baghdad. 2014. Vol. 56, no. 4, pp.401-404.
https://search.emarefa.net/detail/BIM-533384
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 403-404
رقم السجل
BIM-533384
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