Serum carbohydrate antigen-125 levels as a marker in non hodgkin's lymphoma
العناوين الأخرى
مستويات الأنتيجين الكربوهيدارتي-125 كدلالة أورام في متابعة مرضى أورام الغدد اللمفاوية اللاهودجيكينية
المؤلفون المشاركون
Mahran, Taha Zaki Muhammad
Abd al-Latif, Hanan Harith
المصدر
العدد
المجلد 28، العدد 1 (31 يناير/كانون الثاني 2004)، ص ص. 157-166، 10ص.
الناشر
تاريخ النشر
2004-01-31
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الموضوعات
الملخص EN
Sixty-seven patients with newly diagnosed Non Hodgkin's lymphoma (NHL) were included in this study.
Serial measurements of serum carbohydrate antigen 125 (CA-125) levels were studied in conjunction with serum Lactate dehydrogenase (LDH) in monitoring response to treatment.
LDH showed increased levels in 52 out of 67 patients (77.6%).
Ten apparently healthy subjects were studied as a control group.
A total of 36 out of 67 patients (53.7%) had increased serum CA-125 levels.
Increased serum CA-125 levels were significantly associated with advanced stage, higher grade, abdominal serosal involvement, bone marrow involvement and bulky disease.
P values were significant in abdominal involvement and in serosal involvement (P<0.05).
(Elevated serum CA-125 levels were associated with high serum levels of LDH (49.2%) (P values were significant < 0.05).
Of the 36 patients presented with high serum CA-125 levels, 30 patients achieved a complete remission (CR) with normalization of CA-125, four cases achieved partial response and 2 patients had stable disease and-had not achieved normalization of CA-125 levels by the end of treatment.
Conclusion: High serum CA-125 levels were found to be significantly associated with mediastinal, abdominal involvement, high tumor bulk and pleural effusion.
Sensitivity of serum LDH and CA-125 was 83.6% and 66.6% respectively which indicated that the biologic information provided by them are different.
Serum LDH provides a measurement of the tumour load and proliferative activity, while serum CA-125 provides the invasive potential of the tumour
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Mahran, Taha Zaki Muhammad& Abd al-Latif, Hanan Harith. 2004. Serum carbohydrate antigen-125 levels as a marker in non hodgkin's lymphoma. Assiut Medical Journal،Vol. 28, no. 1, pp.157-166.
https://search.emarefa.net/detail/BIM-53481
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Mahran, Taha Zaki Muhammad& Abd al-Latif, Hanan Harith. Serum carbohydrate antigen-125 levels as a marker in non hodgkin's lymphoma. Assiut Medical Journal Vol. 28, no. 1(January 2004), pp.157-166.
https://search.emarefa.net/detail/BIM-53481
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Mahran, Taha Zaki Muhammad& Abd al-Latif, Hanan Harith. Serum carbohydrate antigen-125 levels as a marker in non hodgkin's lymphoma. Assiut Medical Journal. 2004. Vol. 28, no. 1, pp.157-166.
https://search.emarefa.net/detail/BIM-53481
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p.165-166
رقم السجل
BIM-53481
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر