Thyrotoxicosis in Qatar

الملخص EN

The medical records ofI79patients with thyrotoxicosis were studied to determine the causes of thyrotoxicosis seen in our hospitalا'،'ااء• a period of eight years (1984-91) and the outcome of the three available treatments (<)/' patients with G/aves'disease (hyperthyroidism).

Graves'disease ؟»'١٠ diagnosed in 151 (84%) of the pa-tients, toxic muitinodular goiter in 15 (8.5%), toxic adenoma in .4) //'،•ا'،ا%) and thyroiditis in six (3.5%).

Graves ' disease affected women predominantly, the female to male ratio being 3:2.

The age range was from (12- 65) years with « mean age of 35 ±11 years.

Ophthalmopathy was present in 62 (41%) of the patients; goiter was «/ا'،اا;/ in 12 (8%).

Most of the patients received antithyroid drugs as their primary treatment.

Forty one of the patients with Graves'disease had re-ceived anti-thyroid drugs as ///،'/’/•/ا(/»ا////ا' treatment for / ±0.7 years; 28 (68%) relapsed.

Of these /'elapsed patients, 23 (82%) ١١'،'/•،' then treated with radioiodine and three (11%) were treated surgically.

lu a total of 105 (69%) patients with Graves'disease that were treated with radioiodine, 66 (63%) ٠١■،'/•(' cured, hypothyroidism developed in 51(49%), and 20 (19%) needed additional (loses, lu 19 (18%) patients, treated by surgery, 15 (79%) ١١'،'/•،' cured, 3 (16%) (level()/)(’(/ hypothyroidism and one (5%) developed a permanent hypo-calcaemia.

Thyrotoxicosis is a clinical syndrome associated with thy-roid hormone excess from various causes ( l’able ١), the most common cause being Graves' disease (GD), followed by toxic' muitinodular goiter, toxic ;،،lenom;، and thyroiditis' ' 'I'he man-agement آه thyrotoxicosis is determined by its cause.

GD can be treated by the three available modalities of antithyroid drugs, by radioactive iodine (RAI) or by surgery®, all of which can be effective*3*.

Address for correspondence: Dr.

Nabil Isseh, Ml), FACP اا/'ا'،امحااء،' Division, Department of Medicine Hamad Medical Corporation, P.O.

Box 3050, Doha, Qatar