الفعالية المضادة للخصوبة للمستخلص الفينولي لأزهار نبات زهرة الجمال Hibiscus rosa sinensis L. في ذكور الجرذان البيض

الملخص EN

The effect of phenolic extract of Hibiscus rosa-sinensis flower on epididymal sperm characteristics and level of testosterone, LH and FSH in male albino rat was studied.

The study was carried out at the department of Biology, College of education,University of kufa.

Twenty four adult male of rats were divided into tow equal groups (12 / groups).

The first group was investigate with1 ml normal saline and served as a control group.

The second group was investigate orally with dose level of 300 mg / kg phenolic extract of H.r.-sinensis flower for 60 day,.

The treatment resulted in significant reduction in the sperm motility, sperm concentration, sperm viability of the treated group (p < 0.001) when compared with the control and significant increasing (p < 0.001) in the abnormal sperm morphology was observed.

The results showed significant reduction (0.005) in the serum levels of testosterone, FSH and LH compared to control.

These findings suggest that the phenolic extract of Hibiscus rosasinensis possesses suppressive effects on male fertility and could be useful in development of male contraceptive agent.