Selective synthesis of b-unsubstituted meso-aryl substituted tripyrranes in water

الملخص EN

A convenient method for the synthesis of b-unsubstituted meso-aryl substituted tripyrranes was developed.

Pyrrole condensed with aldehyde in acidic aqueous to produce tripyrranes selectively in moderate yield.

The selectivity for tripyrranes depended on the electronic and steric properties of aldehyde, the stoichiometric molar ratio and concentrations of the starting materials.

The title compounds were isolated and characterized by 1H NMR, 13C NMR and HR-MS analysis.