Estimation of plasma concentrations of hepatocyte growth factor in acute leukemia in upper Egypt
المؤلفون المشاركون
Ahmad, Ahmad E.
Abd al-Basir, Khalid A.
Zytun, Samih S.
al-Sinbisi, Muhammad A.
al-Said, Abd al-Rahman A.
المصدر
Egyptian Pediatric Association Gazette
العدد
المجلد 63، العدد 1 (31 مارس/آذار 2015)، ص ص. 12-18، 7ص.
الناشر
تاريخ النشر
2015-03-31
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الموضوعات
الملخص EN
Background : Angiogenesis is a fundamental element during malignant transformation, the induction of angiogenesis has been proposed to be through angiogenic factors such as the hepatocyte growth factor (HGF).
Aim : The aim of the study was to assess plasma concentrations of HGF in acute leukemia in Upper Egypt.
Methods : We performed a cross-sectional study of 90 subjects and divided them into three groups, group I consisted of 30 newly diagnosed acute lymphatic leukemia (ALL) cases, group II consisted of 30 patients with newly diagnosed acute myeloid leukemia (AML) cases and group III consisted of 30 apparently healthy persons as control subjects.
Plasma HGF was measured using the ELISA technique.
Results : Statistical comparison between the mean values of plasma HGF in the three studied groups using the F-test followed by the least significant difference showed a significant difference (F = 77, P = 0.001) between ALL cases and the control group and between AML cases and the control group.
Conclusion : The results of the present study suggest that high plasma HGF may play a significant role in the leukemia process and contribute to the leukemic cell dissemination.
The clinical significance of the increased level of HGF in acute leukemia needs further investigation and may suggest a novel therapeutic approach in this disease.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ahmad, Ahmad E.& Abd al-Basir, Khalid A.& Zytun, Samih S.& al-Sinbisi, Muhammad A.& al-Said, Abd al-Rahman A.. 2015. Estimation of plasma concentrations of hepatocyte growth factor in acute leukemia in upper Egypt. Egyptian Pediatric Association Gazette،Vol. 63, no. 1, pp.12-18.
https://search.emarefa.net/detail/BIM-564927
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ahmad, Ahmad E.…[et al.]. Estimation of plasma concentrations of hepatocyte growth factor in acute leukemia in upper Egypt. Egyptian Pediatric Association Gazette Vol. 63, no. 1 (Mar. 2015), pp.12-18.
https://search.emarefa.net/detail/BIM-564927
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ahmad, Ahmad E.& Abd al-Basir, Khalid A.& Zytun, Samih S.& al-Sinbisi, Muhammad A.& al-Said, Abd al-Rahman A.. Estimation of plasma concentrations of hepatocyte growth factor in acute leukemia in upper Egypt. Egyptian Pediatric Association Gazette. 2015. Vol. 63, no. 1, pp.12-18.
https://search.emarefa.net/detail/BIM-564927
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 17-18
رقم السجل
BIM-564927
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر