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Improvement in glomerular filtration rate may decrease mortality among Type-2 diabetics with chronic kidney disease lacking proteinuria : a retrospective study
المؤلفون المشاركون
Taj al-Din, Bijin
Budhiraja, Pooja
Meister, Edward
Popovtzer, Mordecai
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 26، العدد 4 (31 أغسطس/آب 2015)، ص ص. 702-707، 6ص.
الناشر
تاريخ النشر
2015-08-31
دولة النشر
السعودية
عدد الصفحات
6
التخصصات الرئيسية
الموضوعات
- الكلى
- الأمراض
- وظائف الكلى
- الفحوصات الطبية
- البروتين البولي
- مرض السكري
- مرضى السكري
- المضاعفات(الطب)
- الفشل الكلوي
- التشخيص
الملخص EN
Twenty percent of patients with type-2 diabetes mellitus without albuminuria progress to chronic kidney disease (CKD).
The various factors related to development of CKD, the natural course of renal dysfunction as well as mortality in this sub-group of diabetics has not been studied in detail.
The medical records of 121 patients (all males) above the age of 40 years with type-2 diabetes mellitus and CKD, and without proteinuria, were reviewed in this retrospective study.
The outcomes measured included: (a) all-cause mortality, (b) need for hemodialysis (HD), (c) appearance of proteinuria and (d) trend in kidney function.
The all-cause mortality was 33%, with mean age at death being 75.9 years.
Sixty-three percent of the patients had improvement in estimated glomerular filtration rate (eGFR) at the end of the follow-up period.
The mortality was higher in patients with worsening eGFR compared with those with improvement in eGFR (61% vs 39%, P = 0.040).
5.8% of the patients ended up on HD and 16.51% developed proteinuria at the end of the follow-up period.
Patients who developed proteinuria showed a higher tendency for progression of renal failure.
Multivariate logistic regression for trend toward improving versus worsening of the eGFR revealed no statistically significant predictors.
This observational study suggests that in type-2 diabetic patients with CKD, a substantial number of patients will have improvement in eGFR over time.
Careful search for potential reversible causes of kidney damage could help in reducing mortality.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Taj al-Din, Bijin& Budhiraja, Pooja& Meister, Edward& Popovtzer, Mordecai. 2015. Improvement in glomerular filtration rate may decrease mortality among Type-2 diabetics with chronic kidney disease lacking proteinuria : a retrospective study. Saudi Journal of Kidney Diseases and Transplantation،Vol. 26, no. 4, pp.702-707.
https://search.emarefa.net/detail/BIM-592681
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Taj al-Din, Bijin…[et al.]. Improvement in glomerular filtration rate may decrease mortality among Type-2 diabetics with chronic kidney disease lacking proteinuria : a retrospective study. Saudi Journal of Kidney Diseases and Transplantation Vol. 26, no. 4 (Jul. / Aug. 2015), pp.702-707.
https://search.emarefa.net/detail/BIM-592681
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Taj al-Din, Bijin& Budhiraja, Pooja& Meister, Edward& Popovtzer, Mordecai. Improvement in glomerular filtration rate may decrease mortality among Type-2 diabetics with chronic kidney disease lacking proteinuria : a retrospective study. Saudi Journal of Kidney Diseases and Transplantation. 2015. Vol. 26, no. 4, pp.702-707.
https://search.emarefa.net/detail/BIM-592681
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 706-707
رقم السجل
BIM-592681
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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