Desmopressin, imipramine, and oxybutynin in the treatment of primary nocturnal enuresis : a randomized clinical trial
المؤلفون المشاركون
Sayf Hashimi, Maryam
Zulfaghari, Abbas
Ghurbani, Rahib
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 17، العدد 7 (31 يوليو/تموز 2015)، ص ص. 1-6، 6ص.
الناشر
تاريخ النشر
2015-07-31
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
6
التخصصات الرئيسية
الموضوعات
الملخص EN
Background : Nocturnal enuresis is the most common pediatric urologic problem in outpatient clinics.
Objectives : To assess the effect of various monotherapies, and comparing the effects of desmopressin, imipramine, and oxybutynin in children with enuresis, as well as the influence of socioeconomic and cultural factors of their families on the response and relapse rates.
Patients and Methods: The study was a randomized clinical trial conducted on 92 children aged 5 - 14 years, referred to the pediatric clinic of Semnan University Hospital in Semnan, Iran.
Children with primary nocturnal enuresis were randomly allocated to three different treatment groups: desmopressin (n = 30), imipramine (n = 31), and oxybutynin (n = 31) all for 6 weeks.
The socioeconomic and demographic characteristics of all participants were recorded.
The number of wet nights per week was noted at the end of the 6-week-trial, and children were followed up to three months for relapse.
Results : Children in the oxybutynin group showed a slightly higher response rate (71.0% success) and a lower relapse rate (31.8%), while in the desmopressin group the response and relapse rates were 63.3% and 57.9%, respectively, and in the imipramine group 61.3% and 63.2%, respectively.
However, the difference between the 3 groups in terms of response (P = 0.701) and relapse rates (P = 0.095) was not statistically significant.
Conclusions: There is no significant difference between monotherapy with desmopressin, imipramine or oxybutynin in children with enuresis.
However, oxybutynin showed a higher response rate and a lower relapse rate compared to other medications.
More clinical trials with a larger sample size are needed to clarify these uncertainties.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sayf Hashimi, Maryam& Ghurbani, Rahib& Zulfaghari, Abbas. 2015. Desmopressin, imipramine, and oxybutynin in the treatment of primary nocturnal enuresis : a randomized clinical trial. Iranian Red Crescent Medical Journal،Vol. 17, no. 7, pp.1-6.
https://search.emarefa.net/detail/BIM-593699
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sayf Hashimi, Maryam…[et al.]. Desmopressin, imipramine, and oxybutynin in the treatment of primary nocturnal enuresis : a randomized clinical trial. Iranian Red Crescent Medical Journal Vol. 17, no. 7 (Jul. 2015), pp.1-6.
https://search.emarefa.net/detail/BIM-593699
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sayf Hashimi, Maryam& Ghurbani, Rahib& Zulfaghari, Abbas. Desmopressin, imipramine, and oxybutynin in the treatment of primary nocturnal enuresis : a randomized clinical trial. Iranian Red Crescent Medical Journal. 2015. Vol. 17, no. 7, pp.1-6.
https://search.emarefa.net/detail/BIM-593699
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 5-6
رقم السجل
BIM-593699
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر