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Effect of alcohol on the postnatal development of corpus callosum of albino rat
العناوين الأخرى
تأثير الكحول على تطور الجسم الثفني بعد الولادة في الفئران البيضاء
المؤلفون المشاركون
Salih, Muhammad Nabil Mahmud
Sayyid, Sayyid Anwar
Jawish, Shifa Mustafa Mustafa
Anwar, Rasha Ibrahim
المصدر
العدد
المجلد 24، العدد 3 (31 يوليو/تموز 2000)، ص ص. 61-78، 18ص.
الناشر
تاريخ النشر
2000-07-31
دولة النشر
مصر
عدد الصفحات
18
التخصصات الرئيسية
الموضوعات
الملخص EN
Pregnant female albino rats were allowed free access to 10% ethanol as the only source of liquid starting from day 17 of pregnancy.
Their pups were exposed to the same treatment after weaning.
These pups, together with age matched controls, were sacrificed at 0, 5,10,20,30 and 60 days of age.
Sections of the brain were stained with gallocyanin and Holms silver technique.
Ultrathin sections were prepared from 30 and 60 days old pups for electron microscopy.
In alcohol treated animals the corpus callosum showed a decrease in its thickness especially in the older age groups.
The neuralgia cells appeared to be more densely packed in the newly born rats, while in the older age groups they appeared irregularly arranged with areas of degeneration.
The callosal fibers appeared pale with ill defined outline in the silver stained sections.
Electron microscopic examination revealed that, while in the 60 days old control animals most of the callosal fibers were myelinated, the alcohol treated animals showed many unmyelinated fibers.
The diameter of the myelinated fibers AS well as the number of myelin lamella were significantly reduced in the alcohol treated animals at this age.
The alcohol treated animals showed reduction in the sectional area of the corpus callosum which was significant at 30 & 60 days of age.
The genu showed earlier effects than other parts.
Similar reduction in the sectional area of the cerebral hemisphere appeared in the alcohol treated animals resulting in absence of changes in the volume proportion of the corpus callosum in the cerebral hemisphere in most age groups.
This could indicate that the reduction in the callosal area was a part of the changes taking place in the brain due to alcohol.
Longer period of alcohol exposure (age of 60 days), seems to have affected the corpus callosum more severely than the rest of the brain.
This appeared in the form of significant reduction in the volume proportion of the corpus callosum at this particular age
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Salih, Muhammad Nabil Mahmud& Sayyid, Sayyid Anwar& Jawish, Shifa Mustafa Mustafa& Anwar, Rasha Ibrahim. 2000. Effect of alcohol on the postnatal development of corpus callosum of albino rat. Assiut Medical Journal،Vol. 24, no. 3, pp.61-78.
https://search.emarefa.net/detail/BIM-60305
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Salih, Muhammad Nabil Mahmud…[et al.]. Effect of alcohol on the postnatal development of corpus callosum of albino rat. Assiut Medical Journal Vol. 24, no. 3 (Jul., 2000), pp.61-78.
https://search.emarefa.net/detail/BIM-60305
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Salih, Muhammad Nabil Mahmud& Sayyid, Sayyid Anwar& Jawish, Shifa Mustafa Mustafa& Anwar, Rasha Ibrahim. Effect of alcohol on the postnatal development of corpus callosum of albino rat. Assiut Medical Journal. 2000. Vol. 24, no. 3, pp.61-78.
https://search.emarefa.net/detail/BIM-60305
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 77-78
رقم السجل
BIM-60305
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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