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Influence of intravitreal bevacizumab therapy on the patterns of diabetic maculopathy on optical coherence tomography
المؤلفون المشاركون
Myan, Muhammad Atif
al-Rifi, Muhammad Mumin
المصدر
العدد
المجلد 37، العدد 2 (30 يونيو/حزيران 2015)8ص.
الناشر
تاريخ النشر
2015-06-30
دولة النشر
البحرين
عدد الصفحات
8
التخصصات الرئيسية
الموضوعات
الملخص EN
Objective: To evaluate the effect of intravitreal Bevacizumab (Avastin™) on optical coherence tomography (OCT) patterns of patients with different subtypes of diabetic macular edema (DME).
Setting: Ophthalmology Department, King Hamad University Hospital, Bahrain.
Design: A Retrospective Study.
Method: Seventy-one patients (142 eyes) with clinically significant diabetic macular edema who received intravitreal Bevacizumab therapy for six weeks were included in the study.
Visual acuity and OCT patterns before and after receiving treatment were documented.
Diabetic macular edema was subdivided into four groups: diffuse retinal thickening (DRT), cystoid macular edema (CME), pigment epithelial detachment (PED), and mixed features (both DRT and CME).
Macular thickness, macular volume, and visual acuity before and after treatment were compared.
Result: Changes in patients’ macular thickness and macular volume were significantly different for all four subtypes of DME (p=0.002, p=0.001) after treatment with Bevacizumab.
Compared to CME and PED, eyes with DRT showed the greatest change in macular thickness, macular volume, and visual acuity after receiving intravitreal Bevacizumab.
The change in visual acuity six weeks after treatment was not statistically significant (P= 0.61).
Eyes affected with CME or PED were more likely to persist with chronic DME even after receiving treatment.
Conclusion: Patients with DRT had major benefit from intravitreal Bevacizumab.
The study advocates the sub-classification of DME on OCT scans in order to predict patients’ visual prognosis after receiving intravitreal Bevacizumab.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Myan, Muhammad Atif& al-Rifi, Muhammad Mumin. 2015. Influence of intravitreal bevacizumab therapy on the patterns of diabetic maculopathy on optical coherence tomography. Bahrain Medical Bulletin،Vol. 37, no. 2.
https://search.emarefa.net/detail/BIM-603888
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Myan, Muhammad Atif& al-Rifi, Muhammad Mumin. Influence of intravitreal bevacizumab therapy on the patterns of diabetic maculopathy on optical coherence tomography. Bahrain Medical Bulletin Vol. 37, no. 2 (Jun. 2015).
https://search.emarefa.net/detail/BIM-603888
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Myan, Muhammad Atif& al-Rifi, Muhammad Mumin. Influence of intravitreal bevacizumab therapy on the patterns of diabetic maculopathy on optical coherence tomography. Bahrain Medical Bulletin. 2015. Vol. 37, no. 2.
https://search.emarefa.net/detail/BIM-603888
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-603888
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