Study of serum levels of leptin, C-reactive protein and nutritional status in hemodialysis patients

المؤلفون المشاركون

Hasan Pour, Zahra
Pourmofatteh, Mahla
Karajibani, Mansur
Muntazarifar, Farzaneh

المصدر

Iranian Red Crescent Medical Journal

العدد

المجلد 17، العدد 8 (31 أغسطس/آب 2015)، ص ص. 1-5، 5ص.

الناشر

المستشفى الإيراني

تاريخ النشر

2015-08-31

دولة النشر

الإمارات العربية المتحدة

عدد الصفحات

5

التخصصات الرئيسية

الطب البشري

الموضوعات

الملخص EN

Background: Leptin is secreted by adipose tissue and decreases appetite.

However, the role of leptin in the pathogenesis of hemodialysis (HD)-related malnutrition has not been fully evaluated.

Objectives : The aim of study was to investigate the association between the serum leptin levels, serum C-reactive protein (CRP) levels, and nutritional status in hemodialysis patients.

Patients and Methods: This analytical descriptive study included 45 hemodialysis patients and 40 healthy subjects.

Biochemical parameters and serum leptin levels were measured.

The nutritional status was evaluated using a food frequency questionnaire (FFQ) and the calculation of the body mass index (BMI).

Results : Serum leptin (P < 0.05) and albumin (P < 0.0001) levels and BMI (P < 0.001) of HD patients were significantly lower, while CRP levels were significantly higher than those of controls (P < 0.0001).

HD patients consumed the lower daily servings of the food groups compared to the control subjects (P < 0.0001).

A significant positive correlation between serum levels of leptin and albumin and BMI was demonstrated.

No significant correlations were identified between leptin level, CRP level, and other variables.

Conclusions : The findings suggest that low levels of leptin may be a contributory factor for malnutrition in HD patients.

Further studies are required to ascertain the significance of leptin levels in relation to nutritional factors in hemodialysis patients.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Muntazarifar, Farzaneh& Karajibani, Mansur& Hasan Pour, Zahra& Pourmofatteh, Mahla. 2015. Study of serum levels of leptin, C-reactive protein and nutritional status in hemodialysis patients. Iranian Red Crescent Medical Journal،Vol. 17, no. 8, pp.1-5.
https://search.emarefa.net/detail/BIM-605992

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Pourmofatteh, Mahla…[et al.]. Study of serum levels of leptin, C-reactive protein and nutritional status in hemodialysis patients. Iranian Red Crescent Medical Journal Vol. 17, no. 8 (Aug. 2015), pp.1-5.
https://search.emarefa.net/detail/BIM-605992

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Muntazarifar, Farzaneh& Karajibani, Mansur& Hasan Pour, Zahra& Pourmofatteh, Mahla. Study of serum levels of leptin, C-reactive protein and nutritional status in hemodialysis patients. Iranian Red Crescent Medical Journal. 2015. Vol. 17, no. 8, pp.1-5.
https://search.emarefa.net/detail/BIM-605992

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references : p. 5

رقم السجل

BIM-605992