Response of transplant recipients to influenza vaccination based on type of immunosuppression : a meta-analysis
المؤلفون المشاركون
Afshar, Rida Karbasi
Fadil, Muzhjan
Izadi, Murtada
Khidmat, Husayn
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 26، العدد 5 (30 سبتمبر/أيلول 2015)، ص ص. 877-883، 7ص.
الناشر
تاريخ النشر
2015-09-30
دولة النشر
السعودية
عدد الصفحات
7
التخصصات الرئيسية
الموضوعات
الملخص EN
Influenza vaccination is widely used in transplant recipients, but there is little known about the significance and correlating factors of its effectiveness.
In the current study, we reviewed the existing literature on clinical trials performed in transplant recipients on the effectiveness of influenza vaccination and to evaluate the relevance of the type of immunosuppression employed in these patients on the humoral reaction to the vaccine.
A comprehensive search of the literature was performed through Pubmed and Google Scholar to find reports indicating immunogenicity of influenza vaccination in transplant patients.
Finally, data from 15 published clinical trials were included in the meta-analysis.
Data of 947 transplant recipients retrieved from 15 clinical trials investigating the immunogenicity of influenza vaccination were analyzed in this meta-analysis.
Analysis showed significantly lower rates of sero-conversion among transplant recipients receiving mycophenolate mofetil (MMF) than other immunosuppressive agents (relative risk: 0.724; 95% confidence interval: 0.596–0.880; P = 0.001).
No significant correlation was found with tacrolimus, sirolimus, cyclosporine and azathioprine.
Different immunosuppressive agents seem to have different effects on the humoral response rate to influenza vaccination, with MMF having the most significant deleterious effect.
The limited and controversial data available in the literature do not support any differential effect for other immunosuppressive agents.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Afshar, Rida Karbasi& Izadi, Murtada& Fadil, Muzhjan& Khidmat, Husayn. 2015. Response of transplant recipients to influenza vaccination based on type of immunosuppression : a meta-analysis. Saudi Journal of Kidney Diseases and Transplantation،Vol. 26, no. 5, pp.877-883.
https://search.emarefa.net/detail/BIM-608579
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Afshar, Rida Karbasi…[et al.]. Response of transplant recipients to influenza vaccination based on type of immunosuppression : a meta-analysis. Saudi Journal of Kidney Diseases and Transplantation Vol. 26, no. 5 (Sep. 2015), pp.877-883.
https://search.emarefa.net/detail/BIM-608579
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Afshar, Rida Karbasi& Izadi, Murtada& Fadil, Muzhjan& Khidmat, Husayn. Response of transplant recipients to influenza vaccination based on type of immunosuppression : a meta-analysis. Saudi Journal of Kidney Diseases and Transplantation. 2015. Vol. 26, no. 5, pp.877-883.
https://search.emarefa.net/detail/BIM-608579
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 882-883
رقم السجل
BIM-608579
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر