Ovarian endodermal sinus tumor in pregnancy

الملخص EN

The development of germ cell carcinoma of the ovary during pregnancy is a rare occurrence.

The use of chemotherapeutic drugs in pregnancy is also rare.

Recent advances in chemotherapy have improved significantly the prognosis.

We describe a pregnant patient who found to have endodermal sinus tumor (EST) of the ovary stage IIIc at 14 weeks of gestational age.

She received five courses of post-operative adjuvant multiagent bleomycin, etoposide and platinum chemotherapy and delivered a normal infant, at 35 weeks of gestation by cesarean section.

No residual tumor was found at cesarean section.

After delivery, she received an additional course of chemotherapy.

The infant is developmentally normal at 1-year follow-up.