Expression of MUM1, CD30, CD15 and cd20 by neoplastic cells of lymphomas
المؤلفون المشاركون
al-Karim, Abu al-Qasim Abbas Awad
Abd Allah, Nada Muhammad Ahmad
المصدر
Sudan Journal of Science and Technology
العدد
المجلد 16، العدد 2 (31 ديسمبر/كانون الأول 2015)، ص ص. 98-104، 7ص.
الناشر
جامعة السودان للعلوم و التكنولوجيا عمادة البحث العلمي
تاريخ النشر
2015-12-31
دولة النشر
السودان
عدد الصفحات
7
التخصصات الرئيسية
الموضوعات
الملخص EN
In a descriptive retrospective study aiming to detect MUM1, CD30, CD15 and CD20 expression among lymphoma patients, immunohistochemistry was used.
Thirty formalin fixed paraffin embedded blocks specimens (FFPB) were prepared for this study.
Sections were cut by rotary microtome then stained by immunohistochemical method (new indirect method).
The ages of the involved patients ranged between one year to75 years with mean age 28 (± 23.3) years.
Most of the patients were aggregating at age older than 41 years representing 18 (60 %) and the remaining 12 (40 %) were younger than 41 years.
Twenty (66.7 %) of the patients were males and 10 (33.3 %) were females.
Histopathological diagnosis of the samples revealed diffuse large B-cell non Hodgkin’s lymphoma’s (NHL) in 18 (60%) patients, five (16.7) patients were mantle NHL and the remaining 7 (23.3 %) patients were classical Hodgkin’s lymphoma’s (HL).
MUM1 showed positive expression in 15 (50 %) patients, and negative in 15 (50 %) patients.
The relation between histopathological diagnosis and MUM1 expression showed 10 (66.7 %) positive patients and 8 (53.3 %) negative patients among diffuse large B-cell NHL.
Five (33.3 %) positive patients and 2 (13.3 %) negative patients were classical HL, five (33.3 %) has no reaction with MUM1 protein represented as mantle cell NHL with statistical significance (P value < 0.05).
Among the study subjects CD30 and CD15 were positive in 7 (23.3 %) patients, and negative in 23 (76.7 %) patients.
CD20 was positive in 23 (76.7 %) patients, and negative in 7 (23.3 %) patients.
CD20 status showed positive
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Karim, Abu al-Qasim Abbas Awad& Abd Allah, Nada Muhammad Ahmad. 2015. Expression of MUM1, CD30, CD15 and cd20 by neoplastic cells of lymphomas. Sudan Journal of Science and Technology،Vol. 16, no. 2, pp.98-104.
https://search.emarefa.net/detail/BIM-619143
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Karim, Abu al-Qasim Abbas Awad& Abd Allah, Nada Muhammad Ahmad. Expression of MUM1, CD30, CD15 and cd20 by neoplastic cells of lymphomas. Sudan Journal of Science and Technology Vol. 16, no. 2 (2015), pp.98-104.
https://search.emarefa.net/detail/BIM-619143
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Karim, Abu al-Qasim Abbas Awad& Abd Allah, Nada Muhammad Ahmad. Expression of MUM1, CD30, CD15 and cd20 by neoplastic cells of lymphomas. Sudan Journal of Science and Technology. 2015. Vol. 16, no. 2, pp.98-104.
https://search.emarefa.net/detail/BIM-619143
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 103-104
رقم السجل
BIM-619143
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر