Diabetic glomerulopathy : Pathogenesis and management
المؤلفون المشاركون
Ritz, Eberhard
Schmidt, Susanne
Ismail, Abd Allah
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 11، العدد 3 (30 يونيو/حزيران 2000)، ص ص. 405-413، 9ص.
الناشر
تاريخ النشر
2000-06-30
دولة النشر
السعودية
عدد الصفحات
9
التخصصات الرئيسية
الموضوعات
الملخص EN
Although not all renal disease that diabetic patients develop is due to diabetic glomerulosclerosis, the great majority of patients progressing to advanced renal failure suffer from diffuse or nodular (Kimmelstiel Wilson’s) diabetic glomerulosclerosis.
This condition has become the single most frequent cause of end-stage renal failure in the Western world.
Recent studies indicate that an interplay between genetic predisposition and other factors such as hyperglycemia, blood pressure, age, gender, smoking and ethnicity, predispose to nephropathy both in type 1 and type 2 diabetes mellitus.
It has also become clear that trace albuminuria (“microalbuminuria”) provides a unique opportunity to recognize incipient renal involvement early on, particularly in type 1 and less specifically in type 2 diabetes.
Increasing evidence indicates that early intervention delays progression of nephropathy.
Factors which promote progression of nephropathy include hypertension, proteinuria, smoking, poor glycemic control and, less certainly, high dietary protein intake and hyperlipidemia.
The most important strategies to combat the medical catastrophe of increasing numbers of diabetic patients with end-stage renal failure include (i) prevention of diabetes (mainly type 2), (ii) glycemic control to prevent onset of renal involvement and (iii) meticulous antihypertensive treatment to avoid progression of nephropathy.
Survival of diabetic patients on dialysis and after transplantation is inferior to that of non-diabetic patients, mainly because of high rate of cardiovascular death.
There is consensus that in the absence of major vascular disease the best treatment is renal transplantation in the type 2 diabetic patient and combined kidney and pancreas transplantation in the type 1 diabetic patient.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Schmidt, Susanne& Ismail, Abd Allah& Ritz, Eberhard. 2000. Diabetic glomerulopathy : Pathogenesis and management. Saudi Journal of Kidney Diseases and Transplantation،Vol. 11, no. 3, pp.405-413.
https://search.emarefa.net/detail/BIM-62701
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Schmidt, Susanne…[et al.]. Diabetic glomerulopathy : Pathogenesis and management. Saudi Journal of Kidney Diseases and Transplantation Vol. 11, no. 3 (Dec. 2000), pp.405-413.
https://search.emarefa.net/detail/BIM-62701
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Schmidt, Susanne& Ismail, Abd Allah& Ritz, Eberhard. Diabetic glomerulopathy : Pathogenesis and management. Saudi Journal of Kidney Diseases and Transplantation. 2000. Vol. 11, no. 3, pp.405-413.
https://search.emarefa.net/detail/BIM-62701
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 411-414
رقم السجل
BIM-62701
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر