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Tramadol induced seizure : report of 106 patients
المؤلفون المشاركون
Haghighi, Afshin Borhani
Petramfar, Peyman
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 12، العدد 1 (30 أكتوبر/تشرين الأول 2010)، ص ص. 59-61، 3ص.
الناشر
تاريخ النشر
2010-10-30
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
3
التخصصات الرئيسية
الملخص EN
Background : seizure is one of the possible adverse effects of tramadol hydrochloride, a synthetic, centrally acting analgesic, prescribed for the treatment of moderate to severe pain.
In this study, we describe 106 patients with tramadol induced seizures.
Methods : The patients, who were referred to Nemeses Hospital, Shiraz, Iran, from March 2006 to March 2008, were examined in this cross-sectional study.
All of the patients had experienced seizure (s) after ingesting tramadol.
Each patient was interviewed for demographic data, history of epilepsy, family history of epilepsy, duration of tramadol use, total dose and the last dose of ingested tramadol.
Neurological examinations, routine laboratory tests, electroencephalography, and brain computed tomography were performed for each patient.
Results : one hundred and six patients were studied (102 males and 4 females, mean age : 26.7 ± 6.9 years).
Among them, 92 (86.8%) had new-onset provoked seizure (s) induced by tramadol and in 14 patients (13.2%), tramadol ingestion was considered as a precipitating factor in the setting of previously-known epilepsy.
Tramadol was prescribed by the physicians for alleviation of pain in 20 patients (18.9%) and abused in the remainder (86 patients, 81.1%).
The dose of ingested tramadol before the seizure (s) was 50 to 1500 mg.
Conclusion : tramadol may provoke seizures in patients with epilepsy and also in previously healthy people even within the recommended dose ranges.
Because most of the cases had occurred in young abusers, strategies to prevent tramadol addiction should be sought.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Petramfar, Peyman& Haghighi, Afshin Borhani. 2010. Tramadol induced seizure : report of 106 patients. Iranian Red Crescent Medical Journal،Vol. 12, no. 1, pp.59-61.
https://search.emarefa.net/detail/BIM-63061
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Petramfar, Peyman& Haghighi, Afshin Borhani. Tramadol induced seizure : report of 106 patients. Iranian Red Crescent Medical Journal Vol. 12, no. 1 (Oct. 2010), pp.59-61.
https://search.emarefa.net/detail/BIM-63061
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Petramfar, Peyman& Haghighi, Afshin Borhani. Tramadol induced seizure : report of 106 patients. Iranian Red Crescent Medical Journal. 2010. Vol. 12, no. 1, pp.59-61.
https://search.emarefa.net/detail/BIM-63061
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 61
رقم السجل
BIM-63061
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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