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Vaginal pH as a marker for the perimenopause : A comparison with follicle-stimulating hormone (FSH)
المؤلفون المشاركون
Azzam, Amal Z.
Abu al-Aynayn, Wafa M.
Karkour, Tariq A.
المصدر
Journal of the Medical Research Institute
العدد
المجلد 26، العدد 3 (30 سبتمبر/أيلول 2005)6ص.
الناشر
جامعة الإسكندرية معهد البحوث الطبية
تاريخ النشر
2005-09-30
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background Despite the important implications for women's health and reproduction, little is known about the mechanisms that control and regulate vaginal pH. Aim : the aim of this study is to determine if whether vaginal pH can replace serum Follicle Stimulating Hormone (FSH) as an initial screening test for per menopause. Methods : A cross-sectional com-purgative study was performed on 80 premenopausal women with menopausal symptoms.
Vaginal pH was measured with hydroid strip (range 4.5-7) and serum FSH and oestradiol levels were assayed. Results : All premenopausal women were more evenly distributed across pH categories of 5-6.5.
When vaginal pH was assessed as a predictor for oestradiol status, the sensitivity was 80.88%, specificity 58.33%, positive predictive value (PPV) 91.67%, and the diagnostic accuracy was 77.5%.
The average oestradiol value for women with pH > 4.5 was 22.18 ± 5.98 pg /ml.
When FSH was used as a predictor of oestradiol levels, the sensitivity was 82.35%, specificity 33.33%, PPV was 87.5% and diagnostic accuracy was 75%.
The average FSH value for perimenopausal women with oestradiol <40 pg /ml was 44.24 ±7.4 MIU/ml.
Serum oestradiol showed a significant negative correlation (r = - 0.96 P=0.0001), whereas, serum FSH showed a significant positive correlation (r=0.92, P = 0.0001) with vaginal Ph. Conclusion : vaginal pH is a simple, accurate and cost-effective diagnostic tool for the per menopause.
In the absence of vaginitis, an elevated vaginal pH < 4.5 and serum FSH ≥ 20 MIU/ml are good predictors of low oestradiol level (<40 pg /ml) with nearly similar sensitivity and accuracy.
Hence, vaginal Ph can be a suitable alternative to serum FSH as an initial screening test for per menopause
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Azzam, Amal Z.& Abu al-Aynayn, Wafa M.& Karkour, Tariq A.. 2005. Vaginal pH as a marker for the perimenopause : A comparison with follicle-stimulating hormone (FSH). Journal of the Medical Research Institute،Vol. 26, no. 3.
https://search.emarefa.net/detail/BIM-64461
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Azzam, Amal Z.…[et al.]. Vaginal pH as a marker for the perimenopause : A comparison with follicle-stimulating hormone (FSH). Journal of the Medical Research Institute Vol. 26, no. 3 (2005).
https://search.emarefa.net/detail/BIM-64461
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Azzam, Amal Z.& Abu al-Aynayn, Wafa M.& Karkour, Tariq A.. Vaginal pH as a marker for the perimenopause : A comparison with follicle-stimulating hormone (FSH). Journal of the Medical Research Institute. 2005. Vol. 26, no. 3.
https://search.emarefa.net/detail/BIM-64461
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-64461
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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