Clinical presentation of intraocular retinoblastoma : 5-year hospital-based registry in Egypt

الملخص EN

Purpose : To study the presenting signs of Retinoblastoma in Egypt at Egypt’s main pediatric oncology referral center.

Methods : This is a prospective descriptive study (hospital-based registry) conducted at Children’s Cancer Hospital Egypt between July 2007 and December 2012.

Results : Out of 262 patients diagnosed with retinoblastoma, 244 were suffering from intra-ocular disease at presentation.

One hundred thirty-nine (57 %) patients presented with unilateral disease, while 105 (43 %) suffered bilateral disease.

The mean age at presentation was 20.6± 17 months, averaging 18.87 ± 11.76 months for bilateral and 25.72 ± 18.78 months for unilateral disease.

The most common clinical presentation was leukocoria in 180 (73.8 %) patients, strabismus in 32 (13.1 %) patients and decreased visual acuity in 12 (4.9 %) patients.

Group D and E disease represented 62 % of all affected eyes.

Patients with advanced disease (Group C–E) had longer duration of symptoms.