Dilated cardiomyopathy in a patient with antibody-negative Goodpasture's syndrome and pulmonary relapse
المؤلفون المشاركون
Solak, Yalcin
Selcuk, Nadim Yilmaz
Polat, Ilkers
Atalay, Husayn
Turkmen, Kultigin
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 21، العدد 2 (28 إبريل/نيسان 2010)، ص ص. 332-336، 5ص.
الناشر
تاريخ النشر
2010-04-28
دولة النشر
السعودية
عدد الصفحات
5
التخصصات الرئيسية
الموضوعات
الملخص EN
The Goodpasture's syndrome, also konwn as anti-GBM disease, is an uncommon disease, responsible for 20% of all cases of rapidly progressive glomerulonephritis.
Anti-GBM antibodies are directed against non-collagenous domain (NC-1) of the alpha-3 chain of type IV collagen.
When conventional ELISA assays are used, these antibodies can be detected in almost all the patients.
Nevertheless, some reports have described antibody-negative relapsing disease.
Some aggravating factors, namely, smoking, pulmonary infection and hypervolemia, may expose embedded antigenic target and may be responsible for the relapse.
In addition, these antibodynegative relapses also respond to standard treatment, which comprises of plasma exchange, pulse steroids and cyclophosphamide.
Herein, we report a patient who presented at the Selcuk University Meram School of Medicine, Meram, Konya, Turkey, with the pulmonary-renal syndrome.
He was also found to have idiopathic dilated cardiomyopathy (DCM).
To our knowledge, this is the first report describing co-existence of DCM and anti-GBM disease.
There is growing evidence showing strong relation of both DCM and anti-GBM disease with HLA.
Although not proven, this might have occurred in our patient.
In our opinion, volume overload was facilitated by anuria and DCM and led to an antibody-negative pulmonary relapse.
The relapse was treated just as the first episode and the patient improved satisfactorily.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Solak, Yalcin& Selcuk, Nadim Yilmaz& Polat, Ilkers& Atalay, Husayn& Turkmen, Kultigin. 2010. Dilated cardiomyopathy in a patient with antibody-negative Goodpasture's syndrome and pulmonary relapse. Saudi Journal of Kidney Diseases and Transplantation،Vol. 21, no. 2, pp.332-336.
https://search.emarefa.net/detail/BIM-64941
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Solak, Yalcin…[et al.]. Dilated cardiomyopathy in a patient with antibody-negative Goodpasture's syndrome and pulmonary relapse. Saudi Journal of Kidney Diseases and Transplantation Vol. 21, no. 2 (Apr. 2010), pp.332-336.
https://search.emarefa.net/detail/BIM-64941
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Solak, Yalcin& Selcuk, Nadim Yilmaz& Polat, Ilkers& Atalay, Husayn& Turkmen, Kultigin. Dilated cardiomyopathy in a patient with antibody-negative Goodpasture's syndrome and pulmonary relapse. Saudi Journal of Kidney Diseases and Transplantation. 2010. Vol. 21, no. 2, pp.332-336.
https://search.emarefa.net/detail/BIM-64941
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 335-336
رقم السجل
BIM-64941
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر