Impact of different modes of mechanical ventilation on kidney and liver functions
المؤلفون المشاركون
Fadl Allah, Badr I.
Muhammad, Shirin A. A.
المصدر
Ain Shams Journal of Anesthesiology
العدد
المجلد 6، العدد 3 (31 ديسمبر/كانون الأول 2013)، ص ص. 222-229، 8ص.
الناشر
جامعة عين شمس كلية الطب قسم التخدير
تاريخ النشر
2013-12-31
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الموضوعات
الملخص EN
Background Preclinical and clinical studies suggest that mechanical ventilation contributes to alterations in distant organ function, particularly in the setting of lung-injurious ventilator strategies.
Aim Our goal was to determine the effect of mechanical ventilation with different modes [synchronized intermittent mandatory ventilation (SIMV), continuous positive airway pressure (CPAP), and biphasic intermittent positive airway pressure (BIPAP)] on renal and hepatic functions.
Method This study was a single-blinded controlled study that included 60 patients and was carried out at Al-Zahraa and Al-Hossein University Hospitals with the aim of comparing different modes of mechanical ventilation in critically ill patients with acute lung injury at randomization.
During the first 7 days of mechanical ventilation, the levels of traditional acute kidney injury markers, namely, serum creatinine, urea, creatinine clearance, and urine output (UOP) were determined daily and liver functions tests including liver enzymes (serum glutamic-oxalocetic transaminase, serum glutamic-pyruvic transaminase and alkaline phosphatase) were performed daily.
Results The SIMV and CPAP modes showed a marked and significant impairment in both hepatic and renal function in the form of significant elevation in the levels of liver enzymes (serum glutamic-oxalocetic transaminase, serum glutamic-pyruvic transaminase and alkaline phosphatase) and a significant decrease in the level of renal markers (creatinine clearance and UOP).
However, the BIPAP mode did not show a significant effect on both hepatic and renal functions.
Conclusion In the present study involving critically patients with acute lung injury at the onset of mechanical ventilation, BIPAP mode ventilation reduced the development of acute kidney injury and liver injury compared with the SIMV and CPAP modes.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Fadl Allah, Badr I.& Muhammad, Shirin A. A.. 2013. Impact of different modes of mechanical ventilation on kidney and liver functions. Ain Shams Journal of Anesthesiology،Vol. 6, no. 3, pp.222-229.
https://search.emarefa.net/detail/BIM-650011
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Fadl Allah, Badr I.& Muhammad, Shirin A. A.. Impact of different modes of mechanical ventilation on kidney and liver functions. Ain Shams Journal of Anesthesiology Vol. 6, no. 3 (Sep. / Dec. 2013), pp.222-229.
https://search.emarefa.net/detail/BIM-650011
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Fadl Allah, Badr I.& Muhammad, Shirin A. A.. Impact of different modes of mechanical ventilation on kidney and liver functions. Ain Shams Journal of Anesthesiology. 2013. Vol. 6, no. 3, pp.222-229.
https://search.emarefa.net/detail/BIM-650011
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 229
رقم السجل
BIM-650011
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر